阿托品试验在脑死亡诊断中的价值

为探讨阿托品试验在脑死亡诊断中的价值，对7例呼吸心跳骤停经心肺复苏心跳恢复用呼吸机维持的病人，当GCS评分＜5分开始，每隔6小时作阿托品试验、脑子反射检查、动脉血气分析，并连续心电图、血压、动态脑电图监测。结果：5例脑死亡，阿托品试验都明性；深昏迷时阿托品试验都阳性。脑死亡时阿托品试验增加心率次数与深昏迷时比较，两者差异显著（P＜0．001）。提示每隔6小时作阿托品试验，连续2次阴性结果可作为脑死亡诊断标准之一。

The Diagnostic Value of Atropine Test in Brain Death

To study the standard of brain death diagnosis,we adopt CPR for five patientswith cerebrovascular diseases and two patients,one after stomach major surgery and the oth-er after pancrease major surgery,all having cardiopulmonary arrest to resume heart beat andmaintain mechanical ventilation. At the time when GCS<5 and in the absence of brain stemfunction,we make active electroencephalogram recording with atropin test every six hours.These results show that the patients with deep coma demonstrate atropin test positive andpatients with brain death,negative. The heart rate increase in per minute after atropin test inpatient of deep corna is significantly different from that in patient of brain death (P <0. 001), The findings suggest that the atropine test every six hours yields continously twicethe negative results,which can be regard as one of the brain doath diagnostic standards.