| Acute pancreatitis at the beginning of the 21st century： The state of the art |
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| 作者单位： | Alfredo F Tonsi(Department of General Surgery, East Surrey Hospital, Canada Avenue, Redhill, Surrey, RH1 5RH,United kingdom);Matilde Bacchion,Stefano Crippa,Giuseppe Malleo,Claudio Bassi(Department of Surgery, University of Verona,37134 - Verona, Italy)
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| 摘 要： | Acute pancreatitis is an acute inflammatory disease of the pancreas which can lead to a systemic inflammatory response syndrome with significant morbidity and mortality in 20% of patients. Gallstones and alcohol consumption are the most frequent causes of pancreatitis in adults. The treatment of mild acute pancreatitis is conservative and supportive; however severe episodes characterized by necrosis of the pancreatic tissue may require surgical intervention. Advanced understanding of the pathology, and increased interest in assessment of disease severity are the cornerstones of future management strategies of this complex and heterogeneous disease in the 21st century.
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| 关 键 词： | 急性胰腺炎 炎症反应 手术治疗 胰腺组织 严重程度 疾病 综合征 死亡率 |
| 收稿时间： | 2009 Apr 17 |
Acute pancreatitis at the beginning of the 21st century: The state of the art |
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| Authors: | Alfredo F Tonsi Matilde Bacchion Stefano Crippa Giuseppe Malleo Claudio Bassi |
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| Institution: | Alfredo F Tonsi, Department of General Surgery, East Surrey Hospital, Canada Avenue, Redhill, Surrey, RH1 5RH, United kingdomMatilde Bacchion, Stefano Crippa, Giuseppe Malleo, Claudio Bassi, Department of Surgery, University of Verona, 37134 - Verona, Italy |
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| Abstract: | Acute pancreatitis is an acute inflammatory disease of the pancreas which can lead to a systemic inflammatory response syndrome with significant morbidity and mortality in 20% of patients. Gallstones and alcohol consumption are the most frequent causes of pancreatitis in adults. The treatment of mild acute pancreatitis is conservative and supportive; however severe episodes characterized by necrosis of the pancreatic tissue may require surgical intervention. Advanced understanding of the pathology, and increased interest in assessment of disease severity are the cornerstones of future management strategies of this complex and heterogeneous disease in the 21st century. |
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| Keywords: | Acute necrotizing pancreatitis Systemic inflammatory response syndrome Surgery Pancreatectomy Minimal surgical procedures |
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