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结直肠癌术前~(18)F-FDGPET-CT显像与术后病理分期比较分析
引用本文:张毅勋,;李耀平,;赵铭,;刘海义,;王文渊,;田蓉蓉.结直肠癌术前~(18)F-FDGPET-CT显像与术后病理分期比较分析[J].中华临床医师杂志(电子版),2014(12):22-25.
作者姓名:张毅勋  ;李耀平  ;赵铭  ;刘海义  ;王文渊  ;田蓉蓉
作者单位:[1]山西省肿瘤医院结直肠外科,太原030013; [2]山西省肿瘤医院PET/CT室,太原030013
摘    要:目的探讨18F-FDP PET-CT对结直肠癌术前TNM分期的价值。方法回顾总结术前行PET-CT的30例(33例次)结直肠癌患者,将PET-CT结果与术后手术病理分期结果对比分析。结果检测直肠癌原发灶灵敏度为96.97%;SUVmax为12.26±5.85(5.3128.32)。N分期的灵敏度为88.23%;特异度为69.23%,共提示转移性淋巴结69枚,SUVmax为2.526±2.074(0.2728.32)。N分期的灵敏度为88.23%;特异度为69.23%,共提示转移性淋巴结69枚,SUVmax为2.526±2.074(0.2711.70),淋巴结总检出率为75%,一致率为80%。PET-CT诊断远处转移灶的灵敏度100%、特异度100%、准确性为100%,SUVmax值6.15±3.63(1.8311.70),淋巴结总检出率为75%,一致率为80%。PET-CT诊断远处转移灶的灵敏度100%、特异度100%、准确性为100%,SUVmax值6.15±3.63(1.8315.84)。结论 18F-FDP PET-CT与术后病理比较对结直肠癌进行T分期较为困难,但对于N、M分期有较好的一致性。

关 键 词:结直肠肿瘤  正电子发射断层显像术  体层摄影术  X线计算机

Analysis of the imaging in colorectal carcinoma with18F-FDG PET-CT and its correlation with postoperative pathological staging
Institution:Zhang Yixun, Li Yaoping, Zhao Ming, Liu Haiyi, Wang Wenyuan, Tian Rongrong ( Department of the Colorectal and Anal Surgery, Shanxi Cancer Hospital, Taiyuan 030013, China)
Abstract:Objective To explore the value of clinical staging of colorectal carcinoma with 18F-FDG PET-CT.Methods Clinical data of 30 cases of colorectal carcinoma collected, including PET-CT and pathology, were analyzed retrospectively.Results In 30 patients, the sensitivity of the diagnosis of the primary lesion detection was 96.97%; The maximum standardized uptake value(SUVmax) within the lesion were 12.26±5.85; While the accuracy in diagnosis in distant metastasis was 100%; The SUVmax within the lesion were 6.15±3.63; As to diagnosis in N staging,the accuracy was 80%, with 88.23% sensitivity and 69.23% specificity.Conclusion 18F-FDG PET-CT imaging is useful in the clinical N staging and M staging of colorectal carcinoma.
Keywords:Colorectal neoplasms  Positron-emission tomography  Tomography  X-ray computed
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