|
|||||
|
|
Synthesis and antimycobacterial activity of a series of ferrocenyl derivatives |
|
| Authors: | Maguene Gabin Mwande Jakhlal Jouda Ladyman Melissa Vallin Aurélie Ralambomanana Dimby Andrianina Bousquet Till Maugein Jeanne Lebibi Jacques Pélinski Lydie |
| Affiliation: | a Université Lille Grand Nord, Université de Lille 1, Unité de Catalyse et de Chimie du Solide, UMR CNRS 8181, ENSCL, B.P. 108, 59652 Villeneuve d’Ascq, France b Laboratoire de Bactériologie, CHU de Bordeaux, Hôpital du Haut-Lévêque, Avenue de Magellan, 33604 Pessac, France c Université des Sciences et Techniques de Masuku, Franceville, Gabon |
| Abstract: | In this work we reported the synthesis and evaluation of Mycobacterium tuberculosis activities in vitro of a series of twenty five ferrocenyl derivatives: ferrocenyl amides derived from nicotinamide and pyrazinamide, ferrocenyl pyridinyl, quinolyl and acridinylhydrazones. In particular ferrocenyl acylhydrazones 7 and 8 and ferrocenylquinoxaline amide 57 showed interesting antimycobacterial activities. |
| Keywords: | Ferrocene Synthesis Antitubercular activity Mycobacterium tuberculosis |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |