| 南极海洋丝状真菌多样性及其次级代谢产物的研究进展 |
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| 引用本文： | 李慧,车茜,李德海,顾谦群,朱天骄.南极海洋丝状真菌多样性及其次级代谢产物的研究进展[J].中国海洋药物,2016,35(1):74-81. |
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| 作者姓名： | 李慧 车茜 李德海 顾谦群 朱天骄 |
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| 作者单位： | 中国海洋大学 医药学院 海洋药物教育部重点实验室,中国海洋大学 医药学院 海洋药物教育部重点实验室,中国海洋大学 医药学院 海洋药物教育部重点实验室,中国海洋大学 医药学院 海洋药物教育部重点实验室,中国海洋大学 医药学院 海洋药物教育部重点实验室 |
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| 基金项目： | 国家自然科学基金项目（面上项目，重点项目，重大项目） |
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| 摘 要： | 海洋真菌由于能够产生结构新颖，活性独特的次级代谢产物，现已成为药物先导化合物的重要来源。南极海洋独特而严酷的自然环境使得真菌在生物物种、活性代谢产物等方面表现出明显的多样性和新颖性，正在成为微生物药物研究新的重要资源。本文对近年来国内外南极海洋丝状真菌多样性及其次级代谢产物的研究进展进行综述。
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| 关 键 词： | 南极海洋丝状真菌 多样性 次级代谢产物 |
| 收稿时间： | 2015/3/11 0:00:00 |
| 修稿时间： | 5/5/2015 12:00:00 AM |
Advance in biodiversity and secondary metabolites of Antarctic marine-derived filamentous fungi |
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| LI Hui,CHE Qian,LI De-hai,GU Qian-qun and ZHU Tian-jiao.Advance in biodiversity and secondary metabolites of Antarctic marine-derived filamentous fungi[J].Chinese Journal of Marine Drugs,2016,35(1):74-81. |
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| Authors: | LI Hui CHE Qian LI De-hai GU Qian-qun and ZHU Tian-jiao |
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| Institution: | Key Laboratory of Marine Drugs of MEC,School of Medicine and Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs of MEC,School of Medicine and Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs of MEC,School of Medicine and Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs of MEC,School of Medicine and Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs of MEC,School of Medicine and Pharmacy,Ocean University of China |
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| Abstract: | Marine-derived filamentous fungi have become an important source of drug leading compounds by their ability to produce novel and bioactive natural products. Unique and harsh environment in Antarctic marine environment made the fungi shown significant novelty and diversity in biological species and secondary metabolite. Antarctic marine filamentous fungi now are becoming a new important resource for drug discovery. In this paper, research in diversity and secondary metabolites of the marine-derived filamentous fungi in Antarctic were reviewed. |
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| Keywords: | Antarctic marine-derived filamentous fungi Diversity Secondary metabolite |
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