胃幽门螺杆菌感染与慢性胃炎镜下表现和消化性溃疡关系的探讨

本文报道用快速尿素酶试验法分析的1 717例慢性胃十二指肠疾病的胃幽门螺杆菌(Helicobacter pylori,HP)的感染情况。结果显示皱襞增粗型胃炎、充血/渗出型胃炎、扁平糜烂型胃炎、隆起糜烂型胃炎、胆汁反流型胃炎、出血型胃炎、皱襞萎缩型胃炎的HP感染率分别为70.00％,49.72％,48.86％,47.37％,41.94％,38.1％,34.48％,但无显著性差异。十二指肠溃疡HP感染率高达71.11％,显著高于胃溃疡的60.83％。男性病人HP感染率为47.8％,显著低于女性病人的63.7％。这表明慢性胃炎胃镜下形态学差异与幽门螺杆菌感染率高低无关,十二指肠球部溃疡与HP感染的关系较胃溃疡者更为密切,人群中HP感染存在性别差异。

The Relationship of Helicobacter Pylori and EndoscopyFinding of Chronic Gastritis and Peptic Ulcer

1 717 cases of gastroduodenal disease undergoing routine gas- troscopy were investigated by a rapid urease detecting test for evidence of Helicobacter pylori (HP). The frequency of HP infection of patients with fold hyperdrophic. ery- thematous/exudate, flat erosive, raise erosive, bile reflux, Bleeding, fold atrophic gastritis are 70.00%, 49.72%, 48.86%, 47.37%, 41.94%, 38.1%, 34.48% respec- tively. The prevalence of HP in cases of duodenal ulcer(DU) is 71.11%. While that of gastric ulcer is 60.83%, and the difference between GU and DU is significantly. The rate of HP infection male patients is 47.8% and is significantly lower than that of female patients in which is 63.7%. In conclusion: Lack of association between HP in- fection and the morphologic difference of chronic gastritis; DU is closed relative to HP infection, existence of sexual difference of HP infection in population.