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阻塞性睡眠呼吸暂停低通气综合征患儿扁桃体腺样体切除术后机体免疫功能的变化
引用本文:杨淑娟. 阻塞性睡眠呼吸暂停低通气综合征患儿扁桃体腺样体切除术后机体免疫功能的变化[J]. 临床耳鼻咽喉头颈外科杂志, 2008, 22(17): 785-786
作者姓名:杨淑娟
作者单位:聊城市人民医院耳鼻咽喉科,山东,聊城,252000
摘    要:目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患儿进行扁桃体腺样体切除术后机体免疫功能的变化。方法:检测OSAHS患儿扁桃体腺样体切除术前后血清免疫球蛋白IgG、IgA、IgM及CD3、CD4、CD8的水平,比较患儿术前和术后不同时期血清免疫球蛋白和T淋巴细胞亚群的变化。结果:患儿术后IgG、IgA、IgM及CD3、CD4、CD8的水平有所下降,但与术前相比差异无统计学意义。结论:OSAHS患儿进行扁桃体腺样体切除术对细胞免疫和体液免疫影响不大。儿童时期切除扁桃体和腺样体并不损害宿主免疫的完整性或减少宿主的免疫活力。

关 键 词:睡眠呼吸暂停低通气综合征  阻塞性  免疫功能  儿童  手术治疗

Alteration of the immune function in children with obstruction sleep apnea hypopnea syndrome
YANG Shujuan. Alteration of the immune function in children with obstruction sleep apnea hypopnea syndrome[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2008, 22(17): 785-786
Authors:YANG Shujuan
Abstract:Objective:To study the alteration of the immune function in children with obstructive sleep apnea hypopnea syndrome.Method:The changes of the IgG,IgA,IgM,CD3,CD4 and CD8 levels in serum were observed and analyzed pre and post adenoidectomy and tonsillectomy.Result:Post-operatively,the level of IgG,IgA,IgM,and the CD3,CD4 and CD8 in serum showed no evident alteration.Conclusion:Adenoidectomy and tonsillectomy have no injury on the immune function of children with OSAHS.
Keywords:Obstructive sleep apnea hypopnea syndrome  Immunity function  Child  Surgical operation
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