硒酸酯多糖联合治疗类风湿性关节炎的疼痛症状

目的观察硒酸酯多糖联合类风湿性关节炎(RA)的疗效。方法56例RA患者随机分成两组,治疗组加服硒酸酯多糖胶囊。观察两组的检测指标变化。结果经6周治疗两组患者晨僵时间、关节肿胀指数、关节压痛指数、血沉较治疗前均有显著改善(P<0.05或P<0.01),总有效率治疗组高于对照组(P<0.05),尤其是关节压痛指数治疗前后的差值治疗组高于对照组(P<0.05)。结论硒酸酯多糖是改善RA疼痛症状疗效好、毒副反应轻的协同性治疗药物。

Selenate Lipopolysaccharide combined to treat the ache of rheumatoid arthritis

Objective To observe the clinical effect of selenate lipopolysaccharide combined to treat rheumatoid arthritis(RA).Methods One the foudation of the conventional non-steroid antiinflammatory agents and disease-modifying anti-rheumatic drug,56patients were devided into two groups.The treated group wa s increased to take selenate lipopolysaccharide capsules.The changes o f reated clinical indexes in the two groups were compared.Results After 6weeks treatment,conditiom o f patients in both groups were improv ed in morning stiffness time,joint swollen index as well as ESR level(P<0.05or P<0.01),and the total effective rate higher i n the treated group than those in the c ontrol group(P<0.05),especially the joint tenderness in dex more significantly improved than those of control(P<0.05).Conclusion Selenate lipopolysaccharide has good effect on easing ache of RA with less toxic ad verse reaction,so is worthy of recom mendation.