新诊断2型糖尿病的代谢和慢性并发症分析

目的研究新诊断2型糖尿病患者的代谢控制指标及糖尿病慢性并发症患病率的变化。方法对住院患者进行糖尿病并发症筛查和数据采集。结果 275例患者中,男156例,女119例。患者的发病年龄由2009年的53.3岁±12.5岁,下降到2011年的51.3岁±15.3岁。体质指数:男性从2009年的25.33 kg/m2±3.25 kg/m2增加到2009年的26.15 kg/m2±3.40 kg/m2;腰臀比≥0.90(男性)或≥0.85(女性)的异常率分别从2009年的72%、71.3%和73.6%增加到78.5%、83.4%和82.8%;空腹血糖和HbAlc分别由2009年的9.0 mmol/L±2.5 mmol/L降低到2011年的7.5 mmol/L±1.4 mmol/L;三酰甘油(TG)上升,高密度脂蛋白胆固醇(HDL-C)无明显的变化;血压各年无显著性变化;脑血管病变患病率由2009年的12.6%增加至2011年的24.1%;糖尿病视网膜病变患病率由2009年的38.2%下降至2011年的30.3%;肾病患病率由2009年的32.6%上升至2011年的34.7%;心血管并发症由2009年的27.1%增加至2011年的42.5%;神经病变患病率由2009年的61.8%下降至2011年的52.7%;糖尿病足患病率由2009年的8.1%下降至2011年的5.2%。结论在2009～2011年期间2型糖尿病患者,肥胖人群呈现逐年增多,血糖、血压有所下降,三酰甘油上升;视网膜病变下降、肾病无明显的变化,心脑血管并发症患病率明显增加。

Metabolic Disorders and Chronic Complications in Newly Diagnosed Type 2 Diabetes Mellitus

Objective To investigate the characteristics of metabolic disorders and chronic complications in newly diagnosed type 2 diabetes mellitus.Methods Hospitalized patients with complications of diabetes were screened and made data collection.Results 275 patients with newly diagnosed type 2 diabetes mellitus were studied.Among them,there were 156 male and 119 female.From 2009 to 2011,the age of onset changed from 53.3±12.5 to 51.3±15.3;the BMI changed from 25.33±3.25 kg/m2 to 26.15±3.40 kg/m2;the fasting blood sugar and HbAlc declined from 9.0±2.5 mmol/L TO 7.5±1.4 mmol/L.From 2009 to 2011,the incidence rate of cerebral disease increased from 12.6 to 24.1%;the incidence of diabetic retinopathy and diabetic peripheral neuropathy declined from 38.2% to 30.3%,61.8%to 52.7%;The incidence of diabetic nephropathy and cardiovascular disease increased from 32.6% to 34.7% and 27.1%to 42.5%.Conclusion From 2009 to 2011,obesity has increased,the fasting blood sugar and HbAlc and blood pressure declined,the incidence of diabetic retinopathy and diabetic nephropathy has not changed,but the occurrence of hyperlipoidemia and cardiovascular cerebrovascular complications has increased.