莫西沙星治疗获得性肺炎临床分析

目的探讨莫西沙星治疗获得性肺炎的临床效果。方法收集本院2010年1月～2011年10月治疗的66例获得性肺炎,随机分成观察组和对照组各33例,观察组应用莫西沙星治疗,对照组采用左氧氟沙星治疗,疗程均为10d。结果观察组总有效率100.0%,对照组总有效率81.9%。两组痊愈率、总有效率比较差异有统计学意义（P〈0.01）。两组肺炎克雷伯杆菌、表皮葡萄球菌、卡他球菌、大肠杆菌的清除率均为100.0%,差异无统计学意义（P〉0.05）,但是流感嗜血杆菌、绿脓杆菌、金黄色葡萄球菌、肺炎链球菌清除率比较差异有统计学意义（P〈0.01）。结论莫西沙星治疗获得性肺炎临床疗效好,细菌清除率高,可以推广应用。

Clinical analysis of Moxifloxacin in treatment of acquired pneumonia

Objective To investigate clinical effects of Moxifloxacin in treatment of acquired pneumonia. Methods From January 2010 to October 2011,66 patients with acquired pneumonia were randomly divided into observation group and control group, each group was 33 cases. Observation group were treated with moxifloxacin and control group with levofloxacin,10 days for a course. Results The total effi- ciency of 100. 0% in the observation group and 81.9% in the control group. The total effective rate were significantly different（ P 〈 0. 05 ）. Clearance rate of Klebsiella pneunaoniae, Staphylococcus epidermidis, catarrhal bacteria, E. coli were 100%, there were no significant differ- ence hetween two groups（ P 〉 0.05 ） , but clearance rate of Haemophilus influenzae, Pseudomonas aeruginosa, Staphylococcus aureus, pneu- monia Streptococcus were significantly difference between two groups （ P 〈 0. 01 ）. Conclusion Moxifloxacin have a good clinical efficacy and bacterial eradication rate in treatment of acquired pneumonia, it can be widely used.