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后程适形放疗联合同期化疗治疗中上段食管癌疗效分析
引用本文:魏林,安永恒,陈祥明,程园园. 后程适形放疗联合同期化疗治疗中上段食管癌疗效分析[J]. 泰山医学院学报, 2008, 29(2): 121-123
作者姓名:魏林  安永恒  陈祥明  程园园
作者单位:1. 泰山医学院附属泰安医院肿瘤内科,山东,泰安,271000
2. 青岛大学医学院附属医院肿瘤科,山东,青岛,266000
摘    要:目的探讨后程适形放疗联合同期化疗对中上段食管癌的近期疗效。方法对61例中上段食管癌患者随机分为两组,同期放疗、化疗组(放化组)和单纯放疗组(单放组),均行前程普通放疗加后程适形放疗。前程普通放疗行三野等中心照射,剂量DT40Gy/20次,4周完成;后程适形放疗剂量DT26~30Gy/13~15次,2.5~3周完成。总剂量DT66~70Gy,33~35分次,6.5~7周完成。放化组在放疗开始即行DF方案(顺铂+氟尿嘧啶)化疗,共2周期。结果放化组和单放组1年有效率分别为83.9%(26/31)和63.3%(19/30),放化组发生放射性食管炎、WBC值下降等高于单放组。结论与对照组相比,后程适形放疗同步化疗治疗食管癌明显提高了患者的近期疗效及局部控制率,且正常组织的放射性损伤未明显增加。

关 键 词:食管癌  适形放疗  同步  化疗
文章编号:1004-7115(2008)02-0121-03
修稿时间:2007-11-18

An analysis of treatment effectiveness of late course conformal radiotherapy combined with chemotherapy for mid-upper esophageal carcinoma
WEI Lin,AN Yong-heng,CHEN Xiang-ming,CHENG Yuan-yuan. An analysis of treatment effectiveness of late course conformal radiotherapy combined with chemotherapy for mid-upper esophageal carcinoma[J]. Journal of Taishan Medical College, 2008, 29(2): 121-123
Authors:WEI Lin  AN Yong-heng  CHEN Xiang-ming  CHENG Yuan-yuan
Affiliation:1(1.Dept.of Medical Onlology; Central Hospital of Taian City; Taian 271000; China; 2.Medical School Hospital of Qingdao University; Qingdao 266003; China);
Abstract:Objective: To study the treatment efectiveness of late course conformal radiotherapy combined with chemotherapy for mid-upper esophageal carcinoma.Methods: Sixty-one esophageal carcinoma patients were randomly divided into the two groups: the late course three dimensional conformal radiotherapy combined with chemotherapy group and the control group,with the first phase using conventional technique,40Gy in 20 fractions over 4 weeks and then 26~30 Gy in 13~15 fractions over 2.5~3 weeks as the second phase usi...
Keywords:esophageal carcinoma  conformal radiotherapy  concurrent  chemotherapy
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