| INTERACTION OF CISPLATIN WITH MEMBRANES OF RAT EHRLICH ASCITES TUMOR CELL |
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| 作者姓名： | 陈宝卫 王夔 |
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| 作者单位： | Department of Inorganic Chemistry，National Research Laboratories of Natural and Biomimetic Drugs，Beijing Medical University，Beijing 100083 |
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| 摘 要： | ＩＮＴＥＲＡＣＴＩＯＮＯＦＣＩＳＰＬＡＴＩＮＷＩＴＨＭＥＭＢＲＡＮＥＳＯＦＲＡＴＥＨＲＬＩＣＨＡＳＣＩＴＥＳＴＵＭＯＲＣＥＬＬ￥ＣｈｅｎＢａｏｗｅｉ；陈宝卫；ＷａｎｇＫｕｉ；王夔（ＤｅｐａｒｔｍｅｎｔｏｆＩｎｏｒｇａｎｉｃＣｈｅｍｉｓｔｒｙ，Ｎａｔｉ...
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Interaction of cisplatin with membranes of rat ehrlich ascites tumor cell |
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| Baowei Chen,Kui Wang.INTERACTION OF CISPLATIN WITH MEMBRANES OF RAT EHRLICH ASCITES TUMOR CELL[J].Chinese Journal of Cancer Research,1995,7(1):1-4. |
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| Authors: | Baowei Chen Kui Wang |
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| Institution: | 1. Department of Inorganic Chemistry, National Research Laboratories of Natural and Biomimetic Drugs Beijing Medical University, 100083, Beijing
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| Abstract: | Quenching effects of cis-DDP on fluorescence of membranes of rat Ehrlich ascites tumor cell and binding of cis-DDP with the membranes were studied.The results indicate that cis-DDP can react with tumor cell membrane proteins.If the Pt binding sites were grouped into two types,the apparent stability canstants(K) and number of binding sites(n) are estimated. |
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| Keywords: | Cisplatin Tumor cell membrane Fluorescance |
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