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Ethanol and methadone in man: A possible drug interaction |
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| Authors: | Paul Cushman Mary Jeanne Kreek Enoch Gordis |
| Affiliation: | Department of Medicine, Columbia University and St. Luke''s Hospital Center, New York U.S.A.;Department of Medicine, The Rockefeller University, New York U.S.A.;Department of Medicine, Mount Sinai Services, City Hospital of Elmhurst, New York U.S.A. |
| Abstract: | Possible opiate-ethanol interaction was studied in five selected stable non-alcoholic chronic methadone-maintained patients. Ethanol and methadone levels were determined during oral methadone, ethanol and combined methadone-ethanol tolerance tests. The data do not suggest a significant acute interaction between ethanol and methadone as reflected by the rates of disappearance in the blood. |
| Keywords: | Address correspondence and reprint requests to Paul Cushman Jr. St. Luke's Hospital 113rd St. and Amsterdam Avenue New York N.Y. 10025 U.S.A.. |
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