Prospective comparison of combined <Superscript>18</Superscript>F-FDG and <Superscript>18</Superscript>F-NaF PET/CT vs. <Superscript>18</Superscript>F-FDG PET/CT imaging for detection of malignancy期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Prospective comparison of combined 18F-FDG and 18F-NaF PET/CT vs. 18F-FDG PET/CT imaging for detection of malignancy

Authors:	Frank I. Lin Jyotsna E. Rao Erik S. Mittra Kavitha Nallapareddy Alka Chengapa David W. Dick Sanjiv Sam Gambhir Andrei Iagaru

Affiliation:	(1) Division of Nuclear Medicine, Stanford University Medical Center, 300 Pasteur Dr, Room H-2230, Stanford, CA 94305, USA;(2) Apollo Gleneagles PET-CT Centre, Hyderabad, India;(3) Cyclotron Physics, Molecular Imaging Program at Stanford (MIPS), Stanford, CA, USA;(4) Departments of Radiology, Bioengineering, Materials Science and Engineering, Molecular Imaging Program at Stanford (MIPS), Stanford, CA, USA;

Abstract:	Purpose Typically, ¹⁸F-FDG PET/CT and ¹⁸F-NaF PET/CT scans are done as two separate studies on different days to allow sufficient time for the radiopharmaceutical from the first study to decay. This is inconvenient for the patients and exposes them to two doses of radiation from the CT component of the examinations. In the current study, we compared the clinical usefulness of a combined ¹⁸F-FDG/¹⁸F-NaF PET/CT scan with that of a separate ¹⁸F-FDG-only PET/CT scan.

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