| 肝源性糖尿病维生素D与肝硬化分级相关性研究 |
| |
| 引用本文： | 刘红冬,;张囡囡,;苏言辉. 肝源性糖尿病维生素D与肝硬化分级相关性研究[J]. 中国医师进修杂志, 2014, 0(31): 39-41 |
| |
| 作者姓名： | 刘红冬, 张囡囡, 苏言辉 |
| |
| 作者单位： | [1]山东省枣庄矿业集团滕南医院内分泌科,山东微山277606; [2]山东省枣庄矿业集团中心医院肝病科;,山东微山277606; [3]山东省枣庄市薛城区人民医院内分泌科,山东微山277606; |
| |
| 摘 要： | 目的 探讨维生素D水平与肝硬化分级相关性.方法 收集肝源性糖尿病患者38例,2型糖尿病患者48例,健康对照者30例,监测血清25-（OH） D3水平,并计算Child-Pugh积分,分析肝源性糖尿病发病机制与病情相关性.结果 肝源性糖尿病患者、2型糖尿病患者及健康对照者血清25-（OH）D3水平分别是（38.23±12.47）,（63.33±13.58）,（86.14± 16.25）μmol/L,差异有统计学意义（P＜0.05）;肝源性糖尿病患者血清25-（OH）D3水平与肝硬化Child-Pugh积分呈负相关（r=-0.363,P＜0.05）.结论 低水平维生素D或是肝源性糖尿病患者发病机制之一.
|
| 关 键 词： | 肝硬化 糖尿病,2型 维生素D 肝源性糖尿病 Child-Pugh分级 |
Correlation between vitamin D and liver cirrhosis classification in hepatic diabetes |
| |
| Affiliation: | Liu Hongdong,Zhang Nannan,Su Yanhui. (Department of Endocrinology,Tengnan Hospital of Zaozhuang Mining Group ,Shandong Weishan 277606, China) |
| |
| Abstract: | Objective To observe the correlation between vitamin D and liver cirrhosis classification in hepatic diabetes.Methods Thirty-eight patients with hepatic diabetes,48 patients with type 2 diabetes and 30 cases of healthy controls were collected.The level of serum 25-（OH）D3 was determined,and the Child-Pugh score was calculated.The correlation between pathogenesis and pathogenetic condition of hepatic diabetes was analyzed.Results The levels of serum 25-（OH）D3 in hepatic diabetes patients,type 2 diabetes patients and healthy controls were （38.23 ± 12.47）,（63.33 ± 13.58） and （86.14 ± 16.25） μ mol/L,and there was statistical difference （P 〈 0.05）.There was negative correlation in hepatic diabetes between serum 25-（OH）D3 level and liver cirrhosis Child-Pugh score （r =-0.363,P 〈 0.05）.Conclusion Low level of vitamin D may be one of the pathogenesis of hepatic diabetes. |
| |
| Keywords: | Liver cirrhosis Diabetes mellitus, type 2 Vitamin D Hepatic diabetes Child-Pugh classification |
| 本文献已被 维普 等数据库收录！ |
|
