睑板腺按摩与睑板腺疏通治疗睑板腺功能异常青年干眼患者的疗效观察

目的 了解自行睑板腺按摩与门诊行睑板腺疏通治疗伴睑板腺功能异常的青年干眼患者的疗效.方法 选取伴睑板腺功能异常的青年干眼患者48例,按患者意愿分为两组,其中28例给予自行睑板腺按摩的方法指导（自行按摩组）,每次10 min,每天3次,4周后复诊.20例于眼科门诊由医生表面麻醉下行睑板腺疏通（疏通组）,2,4周后复诊时再疏通,共3次.所有患者均进行相关的健康教育,所有患者于治疗前及治疗4周后行Schirmer Ⅰ试验（SⅠt）,泪膜破裂时间（BUT）,角膜荧光素染色（CFL）检查,并进行比较.结果 两组治疗前BUT、SⅠt、CFL比较差异均无统计学意义（P＞0.05）,两组治疗4周后就诊时均诉眼部症状得到了明显改善,两组治疗前和治疗4周后BUT、CFL比较差异有统计学意义（P＜0.05）.但两组治疗4周后SⅠt、BUT、CFL比较差异无统计学意义（P＞0.05）.结论 伴睑板腺功能异常的青年干眼患者如能正确地自行睑板腺按摩亦可达到有效缓解干眼及改善眼部不适症状的目的.

Efficacy of meibomian gland compression and meibomian gland dredge treatment with dry eye young patients of meibomian gland dysfunction

Objective To understand the efficacy of meibomian gland compression by themselves and outpatient meibomian gland dredge treatment with dry eye young patients of meibomian gland dysfunction.Methods Selected 48 young patients with dry eye of meibomian gland dysfunction,patients were divided into two groups according to the wishes,28 patients were given method guidance of meibomian gland compression by themselves （compression group）,every 10 minutes,three times a day,4 weeks after the referral.Other 20 cases meibomian gland dredge by a doctor at the eye clinic performed under anesthesia （dredge group）,2 weeks,4 weeks after the referral and then dredge,3 times.All patients were given to health education,all patients before treatment and after treatment for 4 weeks underwent Schirmer Ⅰ test （S Ⅰ t）,tear film breakup time （BUT）,corneal fluorescein staining （CFL） examination and compared.Results The level of BUT,S Ⅰ t,CFL before treatment in two groups had no significant difference （P ＞ 0.05）.After treatment for 4 weeks,eye symptom had improved in two groups.The level of BUT,CFL before and after treatment for 4 weeks in two groups had significant difference （P ＜ 0.05）.But the level of S Ⅰ t,BUT,CFL after treatment for 4 weeks between two groups had no significant difference （P ＞ 0.05）.Conclusion Dry eye young patients of meibomian gland dysfunction if they can correctly perform meibomian gland compression by themselves can also be reached effectively alleviate dry eye and ocular discomfort symptom improvement purposes.