核磁共振对原发性脑淋巴瘤的诊断分析

目的分析颅内原发性淋巴瘤的MRI表现,以提高对该病的诊断率。方法回顾性分析11例经病理证实的颅内原发性淋巴瘤的MRI表现。结果单发6例,多发5例,共计18个病灶,病理类型均为B细胞型非霍奇金淋巴瘤。位于幕上脑室周围深部白质12个,占67%;MRI平扫表现为病灶均呈长或等T1、等或短T2信号,增强后病灶呈团块状、结节状明显强化。病灶无囊变、坏死、出血及钙化,发生室管膜下转移2例。结论原发性脑淋巴瘤少见,其MR信号变化、强化及转移等特点在与其他颅内肿瘤鉴别中具有一定的诊断价值。

MRI diagnosis and differentiation of primary lymphoma of the brain

Objective] To analyze MRI features of primary lymphoma of the brain, and to improve the diagnosis and differentiation of the disease. Methods] MRI findings in 11 patients with pathologically proved primary lymphoma of the brain were retrospectively analyzed. Results] The lesions were solitary in 6 cases and multiple in 5 cases. There were 18 lesions in 11 patients. Pathologically, all lesions were non-Hodgkins lymphoma of B cell type. 12 lesions (67%) located in the deep white matter around supratentorial brain ventricle. On MRI, the lesions displayed long or iso-T1 and iso-or short T2 signal, which were enhanced with mass or nodosity after contrast adminstration. The tumor showed no cystic degeneration, no hemorrhage and without calcifications. Metastasis lesions under ependyma were found in two cases. Conclusion] primary lymphoma of the brain is a rare tumor. Its characteristic display of signal variety, enhancement and metastasis provide diagnostic value when differentiated from other intracranial tumors.