上矢状窦血栓形成的临床诊治

目的 探讨上矢状窦血栓形成的临床诊治策略.方法 回顾性分析7例经确诊为上矢状窦血栓形成病例的临床资料,对之早期诊断及治疗措施进行归纳、总结.结果 本组7例病例中有3例为产褥期妇女,其余4例患者无特殊病史,7例患者头颅CT扫描均显示不同程度脑水肿,表现脑沟变窄（7例）,局部脑池受压（5例）甚至消失（2例）,平扫检查显示高密度三角征2例,额叶多发小软化灶3例,合并蛛网膜下腔出血2例.DSA检查上矢状窦不显影2例、显影不均4例,动静脉循环时间延长7例,侧支循环血管扩张迂曲5例.7例患者经治疗后临床症状体征均得到改善,生活可自理,随访3年无死亡病例,无新脑出血病例.结论早期诊断治疗可降低上矢状窦血栓形成的病死率和致残率,明显改善患者预后,对于无合并脑出血的上矢状窦血栓形成患者早期行肝素钙抗凝治疗是一种有效并且安全的治疗方案.

Clinical diagnosis and treatment for superior sagittal sinus thrombosis

Objective To discuss the diagnosis and treatment of superior sagittal sinus thrombosis.Methods The early diagnosis and treatment of superior sagittal sinus thrombosis was induced and summarizd,7 cases in our hospital treated from 2005.6 to 2008.9.were analyzed.Results In this investigation,3 cases were puerperal women,and the other 4 had no special medical history.Brain edema of difference degree was found in all cases on CT scans,including sulcus (7 cases),compression of cistern(5 cases) or even disappeared of cistern(2 cases).CT scanning also revealed dense triangle in 2 cases,multiple small encephalomalacia focus of frontal lobe lesions in 3 cases,and sub-arachnoid hemorrhage(SAH) in 2 cases.The digital subtraction angio-grapby(DSA) also was underwent,of 2 superior sagittal sinus not seen,of 4 appear unevenness,of 7 Arterio-venous circulation delayed and of 5 collateral circulation vasodilatation.After treatment,the clinical symptoms and signs of all patients were improved.All of them could be self-supporting.Followed up for 3 years,the mortality was 0,and no one cerebral hemorrhage again.Conclusion The early diagnosis and treatment of superior sagittal sinus thrombosis could reduce the morbidity and mortality, also could improve prognosis.Especially for the one without cerebral hemorrhage,using heparin at the beginning was an effective and safe way.