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Physical activity and cardiovascular disease prevention in women: A review of the epidemiologic evidence
Authors:SS Bassuk  JE Manson
Institution:1. Department of Physical Therapy and the Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA;2. Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, LA, USA;3. Fisher Institute of Health and Well-Being, Ball State University, Muncie, IN, USA;4. Schoold of Kinesiology and Health Studies, Queen''s University, Kingston, Ontario, Canada;5. School of Medicine, Department of Endocrinology and Metabolism, Queen''s University, Kingston, Ontario, Canada;6. K. G. Jebsen Center of Exercise in Medicine at the Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway;7. School of Human Movement & Nutrition Sciences, University of Queensland, St. Lucia, QLD, Australia;8. Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA;1. Department of Pathology, The University of Hong Kong, Hong Kong, China;2. Department of Pathology, Princess Margaret Hospital, Hong Kong, China;3. Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital, Hong Kong, China;4. Department of Pediatrics, Tseung Kwan O Hospital, Hong Kong, China;1. Division of Cardiology, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, United States;2. Stanford University School of Medicine, Stanford, CA, United States;3. Winston-Salem State University, Winston-Salem, NC, United States;4. Department of Cardiovascular Disease, John Ochsner Heart and Vascular Institute, Ochsner Clinical School, Queensland School of Medicine, New Orleans, LA, United States;5. Quebec Heart and Lung Institute, Quebec City, Canada;6. Department of Physical Therapy and Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, United States;7. Veterans Affairs Medical Center, Washington DC, United States
Abstract:Epidemiologic studies suggest that as little as 30 minutes of moderate-intensity physical activity per day can lower the risk of developing cardiovascular disease in women. Sedentary individuals who become physically active even at older ages derive cardiovascular benefits. Physical activity appears to slow the initiation and progression of CVD through salutary effects not only on adiposity but also on insulin sensitivity, glycemic control, incident type 2 diabetes, blood pressure, lipids, endothelial function, hemostasis, and inflammatory defense systems. Public health initiatives that promote moderate increases in physical activity may offer the best balance between efficacy and feasibility to improve cardiovascular health in sedentary populations.
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