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单侧乳腺癌行预防性对侧乳房切除术的研究进展
引用本文:沈楷文,朱景元,顾喜明,王杰,姚龙迪. 单侧乳腺癌行预防性对侧乳房切除术的研究进展[J]. 国际外科学杂志, 2021, 48(3): 190-194
作者姓名:沈楷文  朱景元  顾喜明  王杰  姚龙迪
作者单位:昆山市中医医院外五科 215300;长兴县中医院甲乳外科,湖州 313000
基金项目:国家自然科学基金(82072909)。
摘    要:为了能够防止对侧乳腺癌的发生从而避免产生相关的治疗和死亡,越来越多的单侧乳腺癌患者接受了预防性对侧乳房切除术(CPM),CPM在高风险人群中已经被认为能够获益,比如对于绝经前的 BRCA1/2基因突变携带者。目前针对 BCRA基因突变接受CPM已经达成了共识,尚无法证明CPM在其他人群中的生存获益,...

关 键 词:乳腺肿瘤  预防性对侧乳房切除术  危险因素  生存

Progress of unilateral breast cancer undergoing contralateral prophylactic mastectomy
Shen Kaicen,Zhu Jingyuan,Gu Ximing,Wang Jie,Yao Longdi. Progress of unilateral breast cancer undergoing contralateral prophylactic mastectomy[J]. International Journal of Surgery, 2021, 48(3): 190-194
Authors:Shen Kaicen  Zhu Jingyuan  Gu Ximing  Wang Jie  Yao Longdi
Affiliation:(Fifth Department of General Surgery,Trodionl Chinese Medicine Hospial of Kunshan,Kunshan 215300,China;Department of Thoracie and Breast Surgery,Traditional Chinese Medicine Hopital of Changxing,Huzhou 313000,China)
Abstract:A growing number of people with unilateral breast eancer have chosen to undergo contralateral prophylactic mastectlomy in order to prevent the occurrence of second primary breast cancer and thus avoid asociated treatment and death.Contralateral prophylactic mastectomy has been considered beneficial in high-risk populations,such as premenopausal BRCA1/2 mutation carriers.As a result,contralateral prophylactic mastectomy acceptance in patients with no such mutation is controversial.Contralateral prophylactic mastectomy can reduce the risk by up to 95%。Therefore,it is very important to.evaluate the risk of contralateral breast cancer and to make appopriate surgiecal treatment.A review of risk factors for contralateral breast cancer and the benefts of contralateral prophylactie mastectomy in patients with unilateral breast cancer is presented.
Keywords:Breast neoplasms  :Contralateral prophylactic matectomy  Risk factors  Survival
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