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肺炎衣原体感染与冠心病相互关系的研究
引用本文:赵春华,张静音,李娜,张培因,刘卓明.肺炎衣原体感染与冠心病相互关系的研究[J].标记免疫分析与临床,2005,12(2):70-72.
作者姓名:赵春华  张静音  李娜  张培因  刘卓明
作者单位:长春市中心医院放免中心,老年病科,吉林,长春,130051
摘    要:探讨肺炎衣原体(CP)感染与冠心病(CHD)的相互关系。应用ELISA法检测150例CHD患者及50名健康者(对照组)血清CP特异性抗体IgG,同时检测超灵敏C反应蛋白(hsCRP)、D二聚体(DDimer)及纤维蛋白降解物(FDP)。CHD患者血清检测结果:CP阳性率占72%;hsCRP阳性率占73%;DDimer、FDP指标在CP阳性组与CP阴性组比,P<0.05。实验证明,CP感染与CHD发病机理存在着一定的关系。

关 键 词:肺炎衣原体  冠状动脉疾病
文章编号:1006-1703(2005)02-0070-03
修稿时间:2004年9月24日

Relation Between Chlamydia Pneumoniae Infection and Coronary Heart Disease
ZHAO Chun-hua,ZHANG Jing-yin,LI Na,et al..Relation Between Chlamydia Pneumoniae Infection and Coronary Heart Disease[J].Labeled Immunoassays and Clinical Medicine,2005,12(2):70-72.
Authors:ZHAO Chun-hua  ZHANG Jing-yin  LI Na  
Abstract:The purpose of this study was to investigate the relation between chlamydia pneumo- niae (CP) infection and coronary heart disease (CHD). CP-specific IgG antibodies were determined in 150 cases of CHD, and 50 healthy control subjects by using enzyme-linked immunosorbent assay (ELISA). Besides, hypersensitive C-reactive protein (hs-CRP), D-dimer and fibrin degradation products(FDP) were also measured. In CHD cases the seropositivity rate for CP was 72%, and that for hs-CRP was 73%. The results of determination of D-dimer and the FDP showed that there was significant difference between the CP-positive group and the CP-negative group(P<0.05).Therefore, certain relation between CP infection and development of CHD might exist.
Keywords:Chlamydia pneumoniae  Coronary disease
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