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A pseudolymphomatous skin reaction secondary to flucloxacillin
Authors:Melzer M  Keane F M  Eykyn S J  Breathnach S M
Affiliation:Department of Microbiology, St Thomas' Hospital, London, UK.
Abstract:We report the first case of a pseudolymphomatous skin reaction precipitated by flucloxacillin. Skin histology was suggestive of a cutaneous lymphoma, and DNA analysis by single stranded conformational polymorphism (SSCP) demonstrated T-cell receptor gamma gene monoclonality. Withdrawal of flucloxacillin led to immediate clinical improvement and gradual resolution of skin rash and lymph nodes.
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