| 绞股蓝减弱四氯化碳所致大鼠肝脏脂质过氧化作用 |
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| 引用本文： | 叶正君,蒙缔亚.绞股蓝减弱四氯化碳所致大鼠肝脏脂质过氧化作用[J].工业卫生与职业病,1998,24(2):74-76. |
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| 作者姓名： | 叶正君 蒙缔亚 |
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| 作者单位： | [1]湖北药检高等专科学校 [2]湖北省农科院测试中心 |
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| 摘 要： | 对绞股蓝（ＧＰ）减弱ＣＣｌ４所致肝脏脂质过氧化作用进行了研究，实验将Ｗｉｓｔａｒ大鼠随机分为四组：Ａ（对照组）；Ｂ（ＣＣｌ４）；Ｃ（ＧＰ）；Ｄ（ＣＣｌ４＋ＧＰ）。结果表明，ＣＣｌ４组的脂质过氧化物（ＬＰＯ）含量明显高于对照组，谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）低于对照组；而同时给予ＧＰ的Ｄ组可减弱ＣＣｌ４诱发的上述作用。提示：ＧＰ能减弱ＣＣｌ４对肝脏的损害。
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| 关 键 词： | 绞股蓝 肝 脂质过氧化 四氯化碳 |
INHIBITORY EFFECT OF GYNOSTEMMA PENTAPHYLLUM(GP) ON LIVER LIPID PEROXIDATION CAUSED BY CCl_4 |
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| Ye Zhenjun et al.INHIBITORY EFFECT OF GYNOSTEMMA PENTAPHYLLUM(GP) ON LIVER LIPID PEROXIDATION CAUSED BY CCl_4[J].Industrial Health and Occupational Diseases,1998,24(2):74-76. |
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| Authors: | Ye Zhenjun |
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| Abstract: | The inhibitory effect of GP on liver lipid peroxidation caused by CCl4 was studied. Wistar ratswere randomly divided into 4 groups:A(control),B (CCl4),C(GP)and D(CCl4 +GP). The contentof lipid peroxide (LPO)increased and the activity of glutathione peroxidase (GSH-Px) decreased inCCl4 group compared with the control group- The lipid peroxidation caused by CCl4 was inhibited byadministering GP simultaneously. The results indicated that GP could decrease liver injury inducedby CCl4. |
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| Keywords: | Gynostemma pentaphyllum Lipid peroxide Glutathione peroxidase |
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