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抗生素混合自体骨治疗胫骨感染骨缺损临床疗效分析
引用本文:王羽凝,郝立波.抗生素混合自体骨治疗胫骨感染骨缺损临床疗效分析[J].山东医药,2010,50(20):29-30.
作者姓名:王羽凝  郝立波
作者单位:中国人民解放军总医院,北京,100853
基金项目:国家自然科学基金资助项目 
摘    要:目的探讨抗生素掺和自体骨治疗胫骨感染性骨缺损的作用和疗效。方法胫骨感染性骨缺损患者24例,骨缺损大小为1.5~4.5 cm,均采用一期局部抗生素骨水泥珠链治疗感染,二期自体骨掺和抗生素植骨治疗。随访2~5 a、平均3.6 a。结果本组24例病例植骨均愈合,愈合率100%;22例感染治愈,治愈率91.7%,2例感染复发,经再次清创后治疗获得成功。结论抗生素掺和自体骨治疗胫骨小范围感染性骨缺损安全有效。

关 键 词:慢性骨髓炎  胫骨骨缺损  抗生素  自体骨

Clinical effect of antibiotic-impregnated autogenic cancellous bone graft on treating of small infected tibial defects
WANG Yu-ning,HAO Li-bo.Clinical effect of antibiotic-impregnated autogenic cancellous bone graft on treating of small infected tibial defects[J].Shandong Medical Journal,2010,50(20):29-30.
Authors:WANG Yu-ning  HAO Li-bo
Institution:WANG Yu-ning,HAO Li-bo(The General Hospital of the People\'s Liberation Army,Beijing 100853,P.R.China)
Abstract:Objective To investigate the effects of antibiotic-impregnated autogenic cancellous bone graft on infection elimination and bone incorporation.Methods Twenty-four patients treated for infected tibial nonunions were evaluated.These patients were managed with local antibiotic bead therapy and staged antibiotic-impregnated autogenous cancellous bone graft.The average follow-up period was 3.6 years(range,2 to 5 years).The bone defects were from 1.5 to 4.5 cm.Results Wound healing and bony union were achieved in...
Keywords:chronic osteomyelitis  infected tibial defect  antibiotics  autogenic bone  
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