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Quantitation of tumor growth in the ears of mice
Authors:Luiz CS Maia  Rosane NM Guerra  Maria ID Rossi
Institution:Centro de Pesquisas Arlindo de Assis da Fundação Ataulpho de Paiva, Av. Almirante Barroso 54/1509, Rio de Janeiro, 20031 R.J., Brazil
Abstract:Transplantation of ascitic P-815 mastocytoma cells intradermally in the ears of syngeneic DBA/2J mice allows a simple and precise quantitation of tumor growth by ear swelling. Tumor growth was retarded and then arrested in allogeneic DBA/1J mice, whereas syngeneic hosts died as a result of tumor dissemination in draining lymph nodes, liver and spleen.
Keywords:mice  tumor  ear swelling
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