| Construction of shRNA Targeted to the Rat Angiotensin Ⅱ Type 1 Receptors and Its RNAi in Cytoplasma |
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| 引用本文： | 肖传实,邱龄,曾秋棠. Construction of shRNA Targeted to the Rat Angiotensin Ⅱ Type 1 Receptors and Its RNAi in Cytoplasma[J]. 华中科技大学学报(医学英德文版), 2006, 26(1): 4-8. DOI: 10.1007/BF02828024 |
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| 作者姓名： | 肖传实 邱龄 曾秋棠 |
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| 作者单位： | Department of Cardiovascular Diseases Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China，Department of Cardiovascular Diseases Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China，Department of Cardiovascular Diseases Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China |
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| 摘 要： | Though remarkable progress has been madeinhypertension mechanisms in the last few decades ,the target of treating essential hypertension is stillfocusing pri marily on the rennin-angiotensin-aldo-sterone system(RAAS) .RAAS promotes vascularsmooth muscle constriction, remodels the struc-ture and function of the vascular system,enhancessodiumreabsorption in the kidney by sti mulatingaldosterone secretion. Therefore , RAAS is a cen-tral regulator of hypertension and plays a key roleinthe path…
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| 关 键 词： | RNA interference hypertension angiotensin Ⅱ receptor vector |
| 收稿时间： | 2005-09-20 |
Construction of shRNA targeted to the rat angiotensin II type 1 receptors and its RNAi in cytoplasma |
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| Xiao Chuanshi,Qiu Ling,Zen Qiutang. Construction of shRNA targeted to the rat angiotensin II type 1 receptors and its RNAi in cytoplasma[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 2006, 26(1): 4-8. DOI: 10.1007/BF02828024 |
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| Authors: | Xiao Chuanshi Qiu Ling Zen Qiutang |
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| Affiliation: | (1) Department of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan, China |
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| Abstract: | |
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| Keywords: | RNA interference hypertension angiotensin II receptor vector |
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