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| 可溶性转铁蛋白受体在慢性肾衰伴缺铁性贫血诊断及治疗中的意义 | |
| 引用本文： | 赵心宇,王玉芝,孟秀香,贾莉,李秋娟,柴英.可溶性转铁蛋白受体在慢性肾衰伴缺铁性贫血诊断及治疗中的意义[J].中国医科大学学报,2006,35(2):189-190. |
| 作者姓名： | 赵心宇 王玉芝 孟秀香 贾莉 李秋娟 柴英 |
| 作者单位： | 1. 中国医科大学附属第二医院检验科,辽宁,沈阳,110004 2. 中国医科大学附属第一医院急诊科 3. 大连医科大学检验医学院 |
| 摘 要： | 目的：探讨可溶性转铁蛋白受体（sTfR）在慢性肾功能衰竭（CRF）伴缺铁性贫血诊断及治疗中的意义。方法：对42例CRF患者。20例健康对照者采用血液自动分析法进行血红蛋白（nb）、红细胞压积（Hct）检测；双吡啶比色法测定血清铁（SI）、总铁结合力（TIBC）；双抗体夹心酶联免疫法测定血清铁蛋白（SF）；生物索-亲和索-酶联免疫法测定sTfR。结果：sTfR在CRF伴缺铁组明显升高；与CRF不伴缺铁组比较有显著性差异（P〈0．01）。结论：血清sTfR含量能更加快速、真实地反映体内铁贮存情况，对患者的诊断、治疗具有重要意义。 |
| 关 键 词： | 慢性肾功能衰竭 可溶性转铁蛋白受体 缺铁性贫血 |
| 文章编号： | 0258-4646(2006)02-0189-02 |
| 收稿时间： | 2005-05-11 |
| 修稿时间： | 2005年5月11日 |
Significance of soluble transferrin receptor in the diagnosis and treatment of chronic renal failure accompanied by iron deficiency anemia |
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| ZHAO Xin-yu,WANG Yu-zhi,MENG Xiu-xiang,JIA Li,LI Qiu-juan,CAI Ying.Significance of soluble transferrin receptor in the diagnosis and treatment of chronic renal failure accompanied by iron deficiency anemia[J].Journal of China Medical University,2006,35(2):189-190. | |
| Authors: | ZHAO Xin-yu WANG Yu-zhi MENG Xiu-xiang JIA Li LI Qiu-juan CAI Ying |
| Institution: | 1. Clinical Laboratory, The Second Affiliated Hospital, China Medical University, Shenyang 110004, China; 2. Department of Emergency, The First Affiliated Hospital, China Medical University; 3. Department of Laboratory Diagnostic Medicine, Dalian Medical University |
| Abstract: | Objective: To explore the significance of soluble transferrin receptor(sTfR) in the diagnosis and treatment of chronic renal failure(CRF) accompanied by iron deficiency anemia(IDA).Methods:Blood autoanalysis,dipyridine colorimetry,enzyme-linked immunosorbent assay(ELISA),and biotin-avidin amplified ELISA were performed to determine the levels of hematoglobin and hematocrit,serum iron and total iron binding capacity,serum ferritin,and sTfR in 42 patients and 20 health controls,respectively.Results:he level of sTfR in patients with CRE accompanied by IRD was significantly higher than that in patients with CRE alone(P<0.01).Conclusion:The level of serum sTfR can quickly and exactly reflect the condition of iron storage in the body and is helpful in the diagnosis and treatment of CRF.\chronic renal failure;soluble tranferrin receptor;iron deficiency anemia |
| Keywords: | chronic renal failure soluble tranferrin receptor iron deficiency anemia |
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