性传播疾病病原检测方法的比较研究

目的回顾总结本科性病门诊的性传播疾病的流行病学资料,比较万倍显微镜与C learview快速诊断试剂盒检测、分离培养及染色涂片检测的检出符合率。方法回顾性调查本科性病门诊自应用万倍显微镜以来的所有病例,分别选取30例患者与C learview快速诊断试剂盒检测、分离培养及染色涂片检测结果进行比较。结果单发性病中以非淋菌性尿道炎菌性尿道炎、淋病、梅毒为主,其发病率分别为38.49%,16.17%和11.83%,其中男性分别为38.00%,16.96%和11.43%;女性分别为39.78%,14.36%和12.64%。复合感染中以淋病合并非淋菌性尿道炎菌性尿道炎为多(1 0.4 4%),其次是非淋菌性尿道炎菌性尿道炎合并梅毒(4.3 9%),非淋菌性尿道炎菌性尿道炎合并生殖器疱疹(2.17%)。万倍显微镜与C learview快速诊断试剂盒检测、分离培养及染色涂片检测的检出符合率达90%以上。结论万倍显微镜具有操作简单,监测范围广、检出率高、费用低等优点,适用于性病门诊对性传播疾病的快速准确诊断。

A Comparative Study on the Methods of Detection of Pathogens in Sexually Transmitted Disease

Objective To learn the prevalence of pathogens for STD and the coincidence rate between CMOS microscope and Clearview rapid diagnostic kit,isolating culture and Gram stain smear.Methods All cases from the initial application of CMOS microscope were investigated retrospectively,30 positive cases were selected respectively to compare with Clearview rapid diagnostic kit,isolating culture and Gram stain smear.Results Nongonococcal urethritis(NGU),gonorrhea urethritis(GU) and syphilis account mainly for the incidence of single STD with 38.49%,16.17%,11.83% respectively,including 38%,16.96%,11.43% male patients and 39.78%,14.36%,12.64% female patients.In multiplicity of infection the incidence of NGU complicated with GU was 10.44%,the incidence of NGU complicated with syphilis was 4.39%,2.17% for NGU with genital herpes.The coincidence rate between CMOS microscope and Clearview rapid diagnostic kit,isolating culture,Gram stain smear was all more than 90%.Conclusion CMOS microscope are suitable for rapid and accurate diagnosis of STD.