类癌致异位促肾上腺皮质激素综合征病例报道

异位促肾上腺皮质激素(ACTH)综合征属库欣综合征的一种特殊类型,其发病机制是非垂体的肿瘤组织分泌过量的具有生物活性的ACTH或ACTH类似物,刺激.肾上腺皮质增生并分泌过量的皮质醇,引起一系列临床症状.本义列举了2例由不同部位类癌所敛的异位ACTH综合征,详细阐述了其临床特征、实验室及影像学检查特点,并总结了在诊治过程中的经验与教训,使临床医生能够对此种疾病有充分的了解,及早诊断和治疗.

Carcinoid and ectopic adrenocorticotropic hormone syndrome

Ectopic adrenocorticotropic hormone (ACTH) syndrome is a special type of Cushing's syndrome. It's characterized by excessive secretion of bioactive ACTH or ACTH analogs by non-pituitory tumors, which can induce the hyperplasia of adrenal and the secretion of excessive cortisol. This article sum-marizes two clinical eases of ectopie ACTH syndrome, and describes the clinical manifestations, laboratory and imaging examination, diagnosis and the treatment of syndrome. This report may help the physicians to fully understand, diagnose and treat this disease in the early stage.