RIFLE标准在连续性肾脏替代治疗治疗急性肾衰竭中的应用

目的 探讨以RIFLE标准分级的急性肾衰竭(ARF)患者行连续性肾脏替代治疗(CRRT)最佳时机的选择,同时评价RIFLE分级和病死率之间的关系.方法 回顾性分析2000至2007年以来103例入住ICU行CRRT治疗的ARF患者.结果 患者30 d总病死率45.6%.按RIFLE标准分级,危险性、损伤、衰竭各级30 d病死率分别为25.0%、20.0%、57.3%.结论 按RIFLE标准,衰竭之前行CRRT治疗能明显提高患者生存率.RIFLE-F组30 d病死率明显高于RIFLE-R组和RIFLE-I组.RIFLE标准适合作为ARF的定义和分级标准.

Application of RIFLE criteria for acute renal failure in patients treated with continuous renal replacement therapy

Objective To determine the optimal timing of treating acute renal failure(ARF)patients in intensive care unit(ICU)with RIFLE(risk of renal failure,iniury to the kidney,failure of kidney function.loss of kidney function and end-stage renal failure)classification using continuous tenal replacement therapy(CRRT).And to evaluate the association between mortality and RIFLE classification in the same patients.Methods Clinical data were collected from 103 ARF patients in ICU from 2000 to 2007.Results The 30-days hospital mortality rate was 45.6%.The 30 days' hospital mortality rates of RIFLE-R.RIFLE-I and RIFLE-F were 25.0%,20.0%and 57.3%respectively.Condusion Survival rate of ARF patients can be manifestly elevated if CRRT is performed before RIFLE-F.The patients in RIFLE-F category have a significantly higher mortality than RIFLE-R and-I patients.The RIFLE criteria is fit for ARF classification system