| 心肺复苏犬血TNF-α、IL-6的变化及其意义 |
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| 引用本文： | 陈晓辉,张弋,江慧琳,许松青,田朝伟,刘炳烦,林佩仪,李燕屏.心肺复苏犬血TNF-α、IL-6的变化及其意义[J].岭南急诊医学杂志,2004,9(2):81-82. |
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| 作者姓名： | 陈晓辉 张弋 江慧琳 许松青 田朝伟 刘炳烦 林佩仪 李燕屏 |
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| 作者单位： | 广州医学院第二附属医院急诊科,510260 |
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| 摘 要： | 目的:检测犬心肺复苏后6h内血TNF-α、IL-6含量的变化。方法:12只健康杂种犬,随机分成两组,实验组(n=6):心跳骤停后予常规心肺复苏术。在心跳骤停模型建立前、复苏成功即时、复苏后1 h、2 h、4 h、6 h取血标本。空白组(n=6):不诱发室颤,取血标本时点与实验组一致。结果:在心跳骤停犬恢复自主循环后2h开始血中TNF-α、IL-6水平出现明显的升高(P<0.05),在一定时间内随着时间的延长而增高。结论:TNF-α、IL-6参与了心肺复苏后再灌注损伤的发生发展过程,干预TNF-α、IL-6将会减轻再灌注损伤的急性炎症反应,提高复苏成功率。
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| 关 键 词： | 心肺复苏 犬 血液 TNF-α IL-6 心跳骤停 再灌注损伤 |
Observation on the Rule of Changes of Serum TNF-α、IL-6 in Dogs of Cardiopulmonary Resuscitation and Their Significance |
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| CHEN Xiao-hui,ZHANG Yi,JIANG Hui-lin,et al..Observation on the Rule of Changes of Serum TNF-α、IL-6 in Dogs of Cardiopulmonary Resuscitation and Their Significance[J].Lingnan Journal of Emergency Medicine,2004,9(2):81-82. |
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| Authors: | CHEN Xiao-hui ZHANG Yi JIANG Hui-lin |
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| Institution: | CHEN Xiao-hui,ZHANG Yi,JIANG Hui-lin,et al. Emergency Department,the Second Affiliated Hospital of Guangzhou Medical College,Guangzhou,510260 |
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| Abstract: | |
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| Keywords: | cardiopulmonary resuscitation reperfusion injury cytokine |
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