复方米非司酮联合微管在早早孕人工流产中的临床应用

目的 研究复方米非司酮联合微管在早早孕人工流产中的临床应用价值.方法 已经确诊为早早孕,B超检查孕囊直径0.5～2.0 cm的孕妇,随机分为观察组118例利用复方米非司酮联合微管进行人工流产,与对照组Ⅰ 120例行药物流产,对照组Ⅱ125例直接用微管进行人工流产作对照,了解孕囊、绒毛排出情况,疼痛程度、手术时间、出血情况、术后月经恢复情况等并进行流产效果评定.结果 疼痛程度手术操作两组差异无显著性(P＞ 0.05),手术时间差异有显著性(P＜0.05),观察组平均手术时间为(2.15±0.45)分,对照组Ⅱ为( 4.25±0.29)分,观察组短于对照组Ⅱ.药物流产组平均阴道流血时间为(15.3±0.9)天,观察组、对照组Ⅱ分别为(5.1±0.5)、(6.2±0.3)d,差异有显著性(P＜0.05),药流组流血时间长.不全流产率:观察组2.5％,对照组Ⅰ 20.8％,对照组Ⅱ5.6％.结论 利用复方米非司酮联合微管进行早早孕人工流产,手术时间短、疼痛轻、出血少、创伤少、不全流产率低、并发症少,值得临床推广应用.

Compound mifepristone combined with microtubules in induced abortion during early pregnancy

Objective To study the clinical value of compound mifepristone combined with microtubules in induced abortion during early pregnancy. Methods Women in early pregnancy with a gestational sac of 0.5 to 2.0cm in diameter on B ultrasound examination were randomly assigned to receive compound mifepristone combined with microtubules for induced abortion （ 118 women, study group ）, medical abortion （ 120 women, control group Ⅰ ）, or direct microtubules for abortion （ 125 women, control group Ⅱ）. Discharge of gestational sac and fluff, pain level, surgical duration, bleeding, and postoperative menstrual restoration were observed and the outcomes of abortion were assessed. Results The pain level did not differ significantly between the two surgical abortion groups （ P 〉 0.05 ） but surgical duration differed significantly （ P 〈 0.05 ）. Average surgical duration was shorter in the study group than in the control group Ⅱ （ 2.15 ± 0.45 ）min vs. （ 4.25 ±0.29 ） min]. Time to vaginal bleeding differed significantly between the medical abortion group and both the study group and the control goup Ⅱ（ 15.3 ± 0.9 ） days vs. （ 5.1 ± 0.5 ）days and （ 6.2 ± 0.3 ）days, P〈 0.05 ）]; medical abortion has a longer bleeding time. The incomplete abortion rate was 2.5% in the study group, 20.8% in the control group Ⅰ, and 5.6% in the control group Ⅱ. Conclusions Compound mifepristone combined with microtubules for induced abortion during early pregnancy has shorter surgerical duration, less pain and bleeding, fewer injuries, lower incomplete abortion rate, and fewer complications. It is worth popularizing clinically.