结肠癌手术108例疗效观察

目的 结合临床实践经验,探讨腹腔镜与开腹手术治疗结肠癌的临床疗效.方法 选取2008年1月-2010年6月期间,我院收治的结肠癌108例为研究对象,采用对照研究,经患者知情同意,将其分为对照组(54例)与观察组(54例),对照组采用开腹手术的方式治疗结肠癌,观察组采用腹腔镜手术的方式治疗结肠癌,比较两组患者治疗后的各项指标,评价两种方法的治疗效果.结果 对照组术中出血量(185.54±10.25)ml、镇痛时间(3.21±0.25)min、胃肠恢复时间(8.02±0.85)h、下床时间(9.61±0.75)h、住院时间(17.41±2.06)d 均明显高于观察组(75.55±8.26)ml、( 1.60±0.03) min、(5.11±0.37)h、(6.09±0.43)h、( 10.74±1.90)d,观察组手术时间(176.35±15.24) min明显高于对照组(145.63±12.34) min,差异均有统计学意义(P＜ 0.05).结论 采用腹腔镜的方式治疗结肠癌,具有术中失血量少,术后恢复快、下床时间早、住院时间短等优点,值得临床推广应用.

The efficacy of surgical treatment for colon cancer in 108 patients

Objective To explore the efficacies of laparoscopic surgery and laparotomy for colon cancer. Methods 108 patients wih colon cancer who had been treated in our hospital during January 2008 to June 2010 were included in this study. Use controlled study. The patients were assigned to receive open surgery （ 54 patients, control group ）, or laparoscopic surgery （ 54 patients, study group ）. Various indexes were compared between the two groups and the efficacies of the two procedures was assessed. All measurement data were expressed by mean ＋ standard deviation and T test was applied. P 〈 0.05 was used as a significant statistical difference. Results Blood loss was marked smaller and time to analgesia, time to gastrointestinal recovery, time to ambulation, and length of hospital stay were obviouly shorter in the study group than in the control group [（ 185.54 ± 10.25） mlvs. （75.55 ± 8.26） ml, （3.21 ± 0.25） min vs.（1.60 ± 0.03） min, （8.02 ± 0.85） h vs.（ 1.60 ± 0.03） h, （9.61 ± 0.75） hvs.（5.11 ± 0.37） h, and （17.41 ± 2.06） d vs.（ 10.74 ± 1.90 ） d; P 〈 0.05]; the surgical duration was significantly longer in the study group than in the control group [（ 145.63 ± 12.34 ） min vsl （ 176.35 ± 15.24 ） min, P 〈 0.05 ）]. Conclusions Laparoscopic treatment for colon cancer has some advantage including less blood loss, rapid postoperative recovery, earlier ambulation, and shorter hospital stay. It is worth popularizing clinically.