立止血治疗急性肺损伤出血的临床观察

目的探讨立止血治疗急性肺损伤出血的临床效果。方法选择2012年2月至2012年9月在我院治疗急性肺损伤出血患者72例,随机分成A(立止血)组38例;B(对照)组34例。两组连续治疗3 d后进行疗效对比,共观察7 d。测量记录治疗前后PT,aPTT、血小板变化,观察过敏及血栓栓塞并发症发生情况。结果 A组总有效率较B组明显增加,差异有统计学意义(P<0.05)。两组PT、aPTT、血小板比较无明显变化,差异无统计学意义(P>0.05)。结论立止血治疗急性肺损伤出血的具有良好的效果和安全性,值得临床推广应用。

The Clinical Observation of Reptilase in the Treatment of Acute lung Injury Hemorrhage

Objective To investigate the clinical effect of Reptilase in the treatment of acute lung inju- ry hemorrhage. Methods In our hospital for treatment of acute lung injury in patients with bleeding 72 cases from February to September in 2012, were randomly divided into A （reptilase） group of 38 cases;B （control） group of 34 cases. Two sets of continuous 3 d after curative effect contrast, were observed in 7 d. Measuring and recording before and after the treatment, PT, aPTT, changes of platelet, allergy and thromboembolic com- plications. Results In A group, the total effective rate was significantly increased in group B, the difference was statistically significant （P 〈 0.05 ）. Two groups of PT, aFTT, no significant changes in platelet, no signifi- cant difference （ P 〉 0.05 ）. Conclusion Reptilase in the treatment of lung injury bleeding has a fine effect and safety of acute, it is worthy of clinical application.