超声与凝血、纤溶指标对下肢深静脉血栓及血栓前状态的评价

目的探讨超声与凝血、纤溶指标对下肢深静脉血栓及血栓前状态的诊断价值。方法根据80例下肢深静脉不同的超声表现，分为3组：①血栓组，②血栓前状态组，③正常组。并将各组反映凝血、纤溶机制的相关指标：D二聚体（D—D）、纤维蛋白（原）降解产物（FDP）、纤维蛋白原（Fbg）、血浆凝血酶原时间（PT）、活化部分凝血活酶时间（aPTT）进行统计学分析。结果D—D、FDP、Fbg等3项指标：血栓组与正常组比较，血栓前状态组与正常组比较，血栓组与血栓前状态组比较，差异均呈显著性（P〈0．01）。结论超声联合凝血、纤溶相关指标有助于下肢深静脉血栓及血栓前状态的诊断。

Evaluation of Ultrasound and Coagulation and Fibrinolysis Indicators in Deep Venous Thrombosis of Lower Extremity and Prethrombotic State

Objective Diagnostic value of ultrasound and coagulation fibrinolysis for deep venous thrombosis of lower extremity and pre thrombotic state was discussed. Methods According to different ultra- sonic findings in 80 cases with lower extremity deep venous, we divided them into three groups, including ① the thrombus group,② the prethrombotic state group,③ the normal group. Then indices of cruor fibrinolysis （D-D,FDP,Fbg,PT and aPTT） were statistically analysed by the ultrasonic imaging. Results There were significant difference of D-D, FDP, Fbg, between the thrombus group and the normal group, the prethrombotic state group and the normal group, the thrombus group and the prethrombotic state group （all P 〈 0.01 ）. Con- clusion Ultrasound combined with coagulation and fibrinolysis related indicators contribute to the diagnosis of deep venous thrombosis and pro thrombotic state.