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Herbal Medicine in the Treatment of Alzheimer’s Disease
作者姓名:WU Jian-guo  WANG Yan-yan  ZHANG Zi-lv  YU Bin
作者单位:Department of Neurosurgery,The Second Hospital of Tianjin Medical University;Tianjin University of Traditional Medicine,Tianjin State Key Laboratory of Modern Chinese Medicine
摘    要:Associated with the aging of our world population is a sharp increase in the incidence of Alzheimer’s disease,which not only poses a significant health issue but also presents a serious social problem.Although pharmacological treatments were developed based on existing hypotheses,the disease pathogenesis remains to be fully elucidated.Given the complexity of Alzheimer’s disease,Chinese herbal medicine appears to have therapeutic potential for Alzheimer’s disease through multi-target and multi-pathway approach at cellular and molecular levels and holistic adjustment of the body at organ system levels.Recently,a significant breakthrough has been made in the research of Chinese medicine for Alzheimer’s disease.In this article,we review the experimental research progress in understanding how Chinese medicine could be used for the treatment of Alzheimer’s disease.

关 键 词:herbal  elucidated  pathogenesis  Radix  holistic  inhibit  amyloid  adjustment  cholinergic  mitochondrial

Herbal Medicine in the Treatment of Alzheimer's Disease
Authors:WU Jian-guo  WANG Yan-yan  ZHANG Zi-lv and YU Bin
Institution:Tianjin University of Traditional Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin (300193), China
Abstract:Associated with the aging of our world population is a sharp increase in the incidence of Alzheimer''s disease, which not only poses a significant health issue but also presents a serious social problem. Although pharmacological treatments were developed based on existing hypotheses, the disease pathogenesis remains to be fully elucidated. Given the complexity of Alzheimer''s disease, Chinese herbal medicine appears to have therapeutic potential for Alzheimer''s disease through multi-target and multi-pathway approach at cellular and molecular levels and holistic adjustment of the body at organ system levels. Recently, a significant breakthrough has been made in the research of Chinese medicine for Alzheimer''s disease. In this article, we review the experimental research progress in understanding how Chinese medicine could be used for the treatment of Alzheimer''s disease.
Keywords:Alzheimer'' s disease  amyloid-25~35 protein  herbal medicine
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