| 硝苯地平与牙周膜增生 |
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| 引用本文： | 冯冬菲. 硝苯地平与牙周膜增生[J]. 中国医药指南, 2008, 6(2): 129-130 |
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| 作者姓名： | 冯冬菲 |
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| 作者单位： | 黑龙江省哈尔滨市儿童医院口腔科,150010 |
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| 摘 要： | 目的:研究硝苯地平是否可以引起牙周膜的增生。方法:选取60只雄性SD大鼠,随机分成对照组、低浓度硝苯地平组和高浓度硝苯地平组,每组再按不同时间分为1天组、3天组、7天组、14天组和21天组。用免疫组化方法结合计算机光密度分析系统检测并比较各组样本Ⅰ型胶原的表达。结果:硝苯地平可以引起牙周膜中胶原表达的增加,但各组间差异无统计学意义。结论:硝苯地平不能引起牙周膜的显著性增生。
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| 关 键 词： | 硝苯地平 牙周膜 增生 胶原 |
| 文章编号： | 1671-8194(2008)1-129-02 |
Nifedipine and periodontal membrane hyperplasy |
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| FENG Dong-fei. Nifedipine and periodontal membrane hyperplasy[J]. Guide of China Medicine, 2008, 6(2): 129-130 |
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| Authors: | FENG Dong-fei |
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| Abstract: | Objective:To study the effect on periodontal membrane hyperplasy of Nifedipine. Methods:The expression of collagen-Ⅰwas examined by immunehistochemical dyeing and analyzed with photodensitometry according to different groups. Results:The expression of collagen-Ⅰincreased after using Nifedipine, but there was not statistically significant exist among different groups. Conclusion:Nifedipine can not induce periodontal membrane hyperplasy obviously. |
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| Keywords: | Nifedipine periodontal membrane hyperplasy collagen |
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