| 蛋白质组学技术在脑缺血研究中的应用进展 |
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| 引用本文： | 高恒,吴江,张世明. 蛋白质组学技术在脑缺血研究中的应用进展[J]. 中国临床神经科学, 2009, 17(3): 324-327 |
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| 作者姓名： | 高恒 吴江 张世明 |
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| 作者单位： | 苏州大学附属第一医院神经外科,215006 |
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| 摘 要： | 通过应用双向凝胶电泳、荧光双向差异凝胶电泳、高效液相色谱分离、联合质谱及蛋白芯片等蛋白质组学技术，对缺血性脑卒中进行基因后产物一蛋白质组学研究，阐述了蛋白改变在脑缺血的发病机制、病理发展及神经修复等方面的发现，以及蛋白质组学技术在脑缺血研究中的作用。
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| 关 键 词： | 蛋白质组学 技术 脑缺血 |
Proteomics Techniques and Their Applications in Cerebral Ischemia Research |
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| GAO Heng,WU Jiang,ZHANG Shi-Ming. Proteomics Techniques and Their Applications in Cerebral Ischemia Research[J]. Chinese Journal of Clinical Neurosciences, 2009, 17(3): 324-327 |
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| Authors: | GAO Heng WU Jiang ZHANG Shi-Ming |
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| Affiliation: | (Department of Neurosurgery, The First Affiliated Hospital of Soochow University, Suzhou 215006, China) |
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| Abstract: | Through applying proteomic techniques, including two-dimensional electrophoresis, fluorescence two-dimensional differential gel electrophoresis, high performance liquid chromatography, associated mass spectrometry and protein chip, in proteomics study of cerebral ischemia stroke, protein changes of etiology, pathology and neuro-reconstruction were found in cerebral ischemia. The proteomic techniques play an important role in these studies. |
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| Keywords: | proteomics technique ischemic stroke |
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