良性前列腺增生症中医证型与西医临床客观指标的相关性研究

目的:分析良性前列腺增生症(BPH)常见中医证型与西医临床客观指标之间的相关性。方法:分为肾阴不足、气滞血瘀、肾阳亏虚、脾气虚弱、湿热下注、肺热气闭、肝郁气滞等7种证型,并对证型与年龄、病程、I-PSS、前列腺体积、残余尿、PSA、最大尿流率相关性进行多因素logistic回归分析。结果:肾阳亏虚证:与年龄正相关,与I-PSS呈负相关,与残余尿量呈正相关;肾阴不足证:与前列腺体积正相关,与I-PSS呈负相关,与最大尿流率呈正相关;脾气虚弱证:与病程呈负相关,与前列腺体积正相关;气滞血瘀证:与病程正相关,与I-PSS呈正相关,与残余尿量呈负相关;湿热下注证:与病程负相关,与前列腺体积呈负相关,与PSA呈正相关,与最大尿流率呈负相关;肝郁气滞证:与年龄呈负相关,与病程呈显著正相关,与前列腺体积呈正相关,与残余尿量呈负相关;肺热气闭证:与年龄呈正相关,与病程呈显著负相关,与最大尿流率呈负相关。结论:BPH中医各证型大部分与年龄、病程、前列腺体积、残余尿、PSA、最大尿流率客观临床指标有密切相关性。

Correlation between TCM Syndromes and Clinical Indices of Benign Prostatic Hyperplasia

Objective ： To investigate the correlations between common syndrome types of traditional Chinese medicine and west-ern medicine clinical objective indicators of benign prostatic hyperplasia and to explore regularity between syndrome type of tradi- tional Chinese medicine and western medicine objective indicators. Methods ： There were 7 kinds of syndrome types, such as kidney Yin deficiency syndrome, qi and blood stasis syndrome, kidney Yang deficiency syndrome, spleen weakness syndrome, heat and dampness syndrome,lung heat closed syndrome,liver depression and qi stagnation syndrome. To understand evolvement rule among different syndrome types, and justify the type and age, course of diseases, prostate volume, urine flow rate, residual urine, PSA and other clinical data correlation to multi - factor logistic regression analysis. Results ： Kidney Yang deficiency syndrome： age was posi- tive, I -PSS was negative, residual urine volume positive. Kidney Yin deficiency syndrome：prostate volume and the maximum urinary flow rate was positive. IPSS was negative. Spleen weakness syndrome：disease course showed negative,prostate volume was positive. Qi and blood stasis syndrome：disease course shows negative,and IPSS was positive, residual urine volume showed negative. Heat and damp syndrome ： disease course showed negative. Prostate volume showed negative and PSA was positive. The maximum urinary flow rate showed negative. Liver depression and qi stagnation syndrome ： age showed negative and disease course was significantly posi- tive. Prostate volume was positive and residual urine volume showed negative. Lung heat closed syndrome：age was positive and dis- ease course showed negative and the maximum urinary flow rate was negative. Conclusion ： Most TCM types of BPH have close corre- lation with age, course of diseases,prostate volume, maximum urine flow rate, residual urine and PSA.