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I148M variant in PNPLA3 reduces central adiposity and metabolic disease risks while increasing nonalcoholic fatty liver disease
Authors:Jin‐Ho Park  BeLong Cho  Hyuktae Kwon  Daria Prilutsky  Jae Moon Yun  Ho Chun Choi  Kyu‐Baek Hwang  In‐Hee Lee  Jong‐Il Kim  Sek Won Kong
Affiliation:1. Informatics Program, Boston Children's Hospital, Boston, MA, USA;2. Department of Family Medicine, Seoul National University Hospital, Seoul, South Korea;3. Department of Family Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, South Korea;4. Center for Biomedical Informatics, Harvard Medical School, Boston, MA, USA;5. School of Computer Science and Engineering, Soongsil University, Seoul, South Korea;6. Samsung Genome Institute, Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, South Korea;7. Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, South Korea;8. Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, South Korea;9. Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Abstract:
Keywords:I148M variant  insulin resistance  nonalcoholic fatty liver disease  obesity  triglyceride
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