Spread of novel expanded-spectrum β-lactamases in Enterobacteriaceae in a university hospital in the Paris area, France |
| |
Authors: | M.-F. Lartigue N. Fortineau P. Nordmann |
| |
Affiliation: | Service de Bactériologie-Virologie, H?pital de Bicêtre, Assistance Publique/H?pitaux de Paris, Faculté de Médecine Paris-Sud, K.-Bicêtre, France. |
| |
Abstract: | In 2002, 28 non-duplicate enterobacterial isolates producing extended-spectrum beta-lactamases (ESBLs) were collected from infected patients at the Bicêtre Hospital in Paris, France. Escherichia coli was the predominant ESBL-positive enterobacterial species, comprising ten (36%) of the isolates. CTX-M enzymes (CTX-M-3, CTX-M-10, CTX-M-14 and CTX-M-15) were produced by 11 (39%) of the isolates (six E. coli, two Enterobacter cloacae, one Enterobacter aerogenes, one Proteus mirabilis and one Citrobacter freundii). Other ESBLs, such as VEB-1 and PER-1, were also detected, but less frequently. |
| |
Keywords: | Antibiotic resistance β-lactamase CTX-M Enterobacteriaceae extended-spectrum β-lactamase resistance |
|
|