| Partial purification and osteoinductive activity of swine bone morphogenetic protein. |
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| 摘 要： | Bone morphogenetic protein (BMP) was isolated from the bone matrix of swine and partially purified by means of differential precipitation and molecular sieve chromatography. The molecular weight of BMP estimated by SDS-gel electrophoresis was 19,000 dalton. Bioassay by implanting two milligrams of BMP fraction into thigh muscles of mice resulted in bone formation in 100% of the experimental animals.
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Partial purification and osteoinductive activity of swine bone morphogenetic protein. |
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| D D Jin,B P Ou. Partial purification and osteoinductive activity of swine bone morphogenetic protein.[J]. Chinese medical journal, 1991, 104(10): 863-867 |
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| Authors: | D D Jin B P Ou |
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| Affiliation: | Department of Orthopedics, Nan Fang Hospital, Guangzhou. |
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| Abstract: | Bone morphogenetic protein (BMP) was isolated from the bone matrix of swine and partially purified by means of differential precipitation and molecular sieve chromatography. The molecular weight of BMP estimated by SDS-gel electrophoresis was 19,000 dalton. Bioassay by implanting two milligrams of BMP fraction into thigh muscles of mice resulted in bone formation in 100% of the experimental animals. |
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