| 急性阑尾炎患者血清免疫抑制酸性蛋白测定的意义 |
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| 引用本文： | 刘学军,檀碧波,韩杰,耿玮. 急性阑尾炎患者血清免疫抑制酸性蛋白测定的意义[J]. 河北医药, 2009, 31(8) |
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| 作者姓名： | 刘学军 檀碧波 韩杰 耿玮 |
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| 作者单位： | 1. 河北省人民医院药剂科,石家庄市,050051
2. 河北省人民医院普外二科,石家庄市,050051 |
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| 摘 要： | 目的 探讨急性阑尾炎(AA)患者血清中免疫抑制酸性蛋白(IAP)水平的变化及意义.方法 检测151例AA患者术前、术后的血清IAP水平、外周血中性粒/淋巴细胞(N/L)比值等指标.结果 AA患者血清IAP水平均较对照组明显升高(P<0.01),坏疽或穿孔性AA较单纯性和化浓性AA组明显升高(P<0.01 ).3组AA患者术后第2天血清IAP水平较术前均有明显升高(P<0.01 );术后第5天有所下降,但仍较对照组为高(P<0.01).AA患者N/L比值明显高于对照组(P<0.01).对术前外周血白细胞计数正常的患者,用IAP和N/L比值联合检测,可提高对不典型急性阑尾炎诊断的准确性.结论 AA患者手术前后IAP检测能准确反映机体免疫抑制的程度,提高诊断准确性,指导临床治疗.
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| 关 键 词： | 急性阑尾炎 免疫抑制酸性蛋白 中性粒/淋巴细胞比值 |
The clinical significance of detection of serum immunosuppressive acidic protein in patients with acute appendicitis |
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| LIU Xuejun,TAN Bibo,HAN Jie,et al.. The clinical significance of detection of serum immunosuppressive acidic protein in patients with acute appendicitis[J]. Hebei Medical Journal, 2009, 31(8) |
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| Authors: | LIU Xuejun TAN Bibo HAN Jie et al. |
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| Affiliation: | LIU Xuejun,TAN Bibo,HAN Jie,et al.Department of Pharmacy,Hebei Provincial People's Hospital,Shijiazhuang 050051,China |
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| Abstract: | Objective To investigate the change and its clinical significance of serum immunosuppressive acidic protein(IAP) in patients with acute appendicitis.Methods Serum IAP,leukocyte count and neutrophil: lymphocyte ratio(n:l ratio) were determined in 151 patients with acute appendicitis.Results The IAP levels in patients were significantly higher than those in control group(P<0.01).The IAP levels in patients with gangrenous or perforated appendicitis were significantly higher than those with simple or suppurativ... |
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| Keywords: | acute appendicitis immunosuppressive acidic protein neutrophil:lymphocyte ratio |
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