首页 | 本学科首页   官方微博 | 高级检索  
     

消癌解毒方治疗肠癌术后临床研究
引用本文:周肸,张丹,钱海华,曾莉. 消癌解毒方治疗肠癌术后临床研究[J]. 南京中医药大学学报, 2020, 36(6): 826-830
作者姓名:周肸  张丹  钱海华  曾莉
作者单位:1.南京中医药大学第一临床医学院,江苏 南京 210023
摘    要:目的 观察消癌解毒方对结直肠癌术后患者生活质量及化疗副作用的影响。方法 选取南京中医药大学附属医院肛肠科结直肠癌术后住院患者单盲随机分为对照组与治疗组各30例。对照组予术后肿瘤化疗和心理干预,治疗组在对照组治疗基础上,加服消癌解毒方。治疗12周后观察2组心理状态、生活质量、外周血细胞水平、免疫球蛋白水平、炎症细胞因子水平、肝功能损伤程度。结果 治疗后治疗组部分心理状态因子、卡氏评分等级明显改善(P<0.05~0.01),优于对照组(P<0.01);治疗组外周血细胞检验结果没有明显变化,优于对照组(P<0.05~0.01);治疗组白细胞介素1β(IL-1β)、肿瘤坏死因子-α(TNF-α)表达明显下降(P<0.01),优于对照组(P<0.01);治疗组肝功能损伤情况明显轻于对照组(P<0.05)。结论 消癌解毒方能够改善结直肠癌术后患者的心理状态及生活质量、减轻化疗的不良反应。 

关 键 词:消癌解毒方   结直肠癌   心理干预

Clinical Study of Xiaoai Jiedu Decoction in the Treatment of Postoperative Colon Cancer
ZHOU Xi,ZHANG Dan,QIAN Hai-hu,ZENG Li. Clinical Study of Xiaoai Jiedu Decoction in the Treatment of Postoperative Colon Cancer[J]. Journal of Nanjing University of Traditional Chinese Medicine(Natural Science), 2020, 36(6): 826-830
Authors:ZHOU Xi  ZHANG Dan  QIAN Hai-hu  ZENG Li
Affiliation:1.The First School of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China2.The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China
Abstract:OBJECTIVE To observe the effects of Xiaoai Jiedu Decoction on the quality of life and side effects of chemotherapy in patients with colorectal cancer after surgery. METHODS Inpatients with colorectal cancer in the Anorectal Department, Affiliated Hospital of Nanjing University of Chinese Medicine were selected and single-blind randomly divided into the control group and the treatment group with 30 cases each. The control group received postoperative tumor chemotherapy and psychological intervention, and the treatment group was treated with Xiaoai Jiedu Decoction based on the treatment of the control group. After 12 weeks of treatment, the psychological status, quality of life, levels of peripheral blood cells, immunoglobulin, inflammatory factors, and liver function damage were detected in the two groups. RESULTS After treatment, partial mental state factors, Karnofsky scores in the treatment group were improved, and better than those in the control group (P<0.05,P<0.01). Besides, the peripheral blood cell levels showed no significant change in the treatment group, better than those in the control group (P<0.05,P<0.01). The inflammatory factor levels of interleukin 1β (IL-1β) and tumor necrosis factor-α (TNF-α) notably decreased (P<0.01), better than the control group (P<0.01). The liver damage levels in the treatment group were better than those in the control group (P<0.05). CONCLUSION Xiaoai Jiedu Decoction can improve the mental state and quality of life of patients with colorectal cancer after surgery as well as reduce the adverse effects of chemotherapy. 
Keywords:Xiaoai Jiedu Decoction   colorectal cancer   psychological intervention
点击此处可从《南京中医药大学学报》浏览原始摘要信息
点击此处可从《南京中医药大学学报》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号