| 活体核素示踪神经受体研究进展 |
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| 引用本文： | 王荣福,刘萌. 活体核素示踪神经受体研究进展[J]. 北京大学学报(医学版), 2007, 39(5): 550-554 |
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| 作者姓名： | 王荣福 刘萌 |
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| 作者单位： | (北京大学第一医院核医学科,北京 100034) |
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| 基金项目： | 国家自然科学基金 , 国家重点基础研究发展计划(973计划) , 面向21世纪教育振兴行动计划(985计划) |
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| 摘 要： | 受体研究在脑功能研究中占据重要地位,其中核医学神经受体显像能对活体脑内受体的分布、密度以及生理病理条件下不同活动状态等进行可视化研究已成为当今热门的研究课题,其方法学上的应用与研究成果促进了脑科学的发展与进步.
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| 关 键 词： | 放射性核素显像 受体 感觉 正电子发射断层显像术 |
| 文章编号： | 1671-167X（2007）05-0550-05 |
| 修稿时间： | 2007-04-12 |
Study on neuroreceptor imaging with radionuclide tracing in vivo |
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| WANG Rong-fu,LIU Meng. Study on neuroreceptor imaging with radionuclide tracing in vivo[J]. Journal of Peking University. Health sciences, 2007, 39(5): 550-554 |
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| Authors: | WANG Rong-fu LIU Meng |
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| Affiliation: | Department of Nuclear Medicine,Peking University First Hospital,Beijing 100034,China |
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| Abstract: | SUMMARY Neuroreceptor imaging with radionuclide tracing in vivo has been greatly developed recently.Distribution,density,and activity of receptors in the brain can be visualized by the radioligands labeled for emission computed tomography(ECT),including PET(positron emission tomography)and SPECT(single photon emission computed tomography).The functional and quantitative imaging for several receptors,such as dopamine receptors,serotonin receptors,cholinergic receptors,benzodiazepine receptors,and opioid receptors,has clinical importance.The preparation of receptor imaging agents,foundation of the physio-mathematical model,and the development of nuclear medicine instruments are the main points.In the present review,we will concentrate on introducing the development of brain receptor imaging. |
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| Keywords: | Radionuclide imaging Receptors sensory Positron-emission tomography |
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