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Health concerns predicts poor quality of life in well-controlled epilepsy
Authors:Erik Hessen  Morten I Lossius  Leif Gjerstad  
Institution:aDepartment of Neurology, Akershus University Hospital, 1478 Lørenskog, Norway;bHelse Øst Health Services Research Centre, Akershus University Hospital, Norway;cNational Center for Epilepsy, Rikshospitalet, University of Oslo, Norway;dDepartment of Neurology, Rikshospitalet, Norway;eUniversity of Oslo, Norway
Abstract:PurposeMost studies of quality of life (QOL) in seizure-free epilepsy patients suggest normal or near-normal function. Previous studies on QOL in well-controlled epilepsy have not investigated determinants for QOL from a database that includes a wide range of health related and epilepsy related variables, as well as demographical data, neuropsychological data, data from a comprehensive personality inventory and results from a QOL-questionnaire. Thus, the aim of this study was to analyze predictors of QOL based on such a range of variables.MethodsAdults with epilepsy on antiepileptic (AED) monotherapy and without epileptic seizures for at least 2 years (n = 158) were assessed with the QOLIE-89.ResultsThe main findings were that QOL in well-controlled epilepsy patients was in the normal range and that presence of substantial health related concerns was a significant predictor of poor QOL.DiscussionThe findings that substantial health concerns predict poor QOL may have clinical implications, as seizure-free epilepsy is a relatively benign condition, and careful information and counselling about this may alleviate health concerns and improve quality of life.
Keywords:Epilepsy  Seizure free  Quality of life  QOLIE-89  MMPI-2
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