| ACE,LDH活性和MDA含量在实验性ARDS大鼠小肠中的变化 |
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| 引用本文： | 刘红英,克拉拉·阿巴斯,张丽,张艳红. ACE,LDH活性和MDA含量在实验性ARDS大鼠小肠中的变化[J]. 临床军医杂志, 2005, 33(2): 140-142 |
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| 作者姓名： | 刘红英 克拉拉·阿巴斯 张丽 张艳红 |
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| 作者单位： | 解放军第546医院,内科,新疆,马兰,841700;新疆医科大学基础医学院,病理生理教研室,新疆,乌鲁木齐,830000, |
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| 摘 要： | 目的观察急性呼吸窘迫综合征(ARDS)肠损伤中血管紧张素转换酶(ACE),乳酸脱氢酶(LDH)活性和丙二醛(MDA)含量变化,研究ARDS发病机制。方法采用尾静脉注射油酸法复制大鼠ARDS模型,测血清、肠组织匀浆ACE、LDH活性和MDA含量。结果血清、肠组织匀浆ACE,LDH活性和MDA含量均出现变化。结论血浆和组织匀浆中的ACE,LDH活性和MDA含量变化可在一定程度上反映病情的轻重,对预后有一定的提示作用。
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| 关 键 词： | 小肠 大鼠 急性呼吸窘迫综合征 血管紧张素转换酶 乳酸脱氢酶 丙二醛 |
| 文章编号： | 1671-3826(2005)02-0140-03 |
| 修稿时间： | 2005-01-19 |
The Alteration of ACE and LDH Activity and MDA in the Small Intestine of Rats During Acute Respiratory Distress Syndrom |
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| Liu Hong-yin,Ke La-la,Zhang Li,Zhang Yan-hong. The Alteration of ACE and LDH Activity and MDA in the Small Intestine of Rats During Acute Respiratory Distress Syndrom[J]. Clinical Journal of Medical Officer, 2005, 33(2): 140-142 |
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| Authors: | Liu Hong-yin Ke La-la Zhang Li Zhang Yan-hong |
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| Abstract: | Objective To investigate into the alteration of angiotensin converting enzyme (ACE) and lactic dehydrogenase (LDH) activity and malondialdehyde (MDA) content in the small intestine during acute respiratory distress syndrome (ARDS) and explore the mechanism of ARDS.Methods ARDS rat models were established by injecting oleic acid into the veins of the tails. Plasma and the small intestine homogenate's ACE and LDH activity and MDA content were assessed during the experimental hours. Results There were alteration of index in ACE and LDH activity and MDA content.Conclusion The alteration of ACE and LDH activity and MDA content can reflect the condition and forecast the result of the disease to some extent. |
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| Keywords: | small intestine rat acute respiratory distress syndrome angiotensin converting enzyme lactic dehydrogenase malondialdehyde |
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