Unusual etiology of visual loss in an HIV-infected patient due to endogenous endophthalmitis |
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| Authors: | P. Miailhes ,M. Labetoulle,T. Naas,M. Guibert,P. Bouré e,E. Frau,P. Nordmann, P. Galanaud |
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| Affiliation: | Department of Internal Medicine, Hôpital Antoine Béclère, Clamart,;Department of Hepatogastroenterology, Hôtel-Dieu, 1 place de l'hôpital, 69288 Lyon cedex 2,;Department of Ophtalmology, Hôpital de Bicêtre, Le Kremlin-Bicêtre,;Department of Bacteriology–Virology–Parasitology, Hôpital de Bicêtre, Le Kremlin-Bicêtre and;Department of Bacteriology–Virology, Hôpital Antoine Béclère, Clamart, France;Tel: +33 4 72 41 30 95;Fax: +33 4 72 41 31 40E-mail: |
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| Abstract: | Disseminated candidiasis, especially ocular infections such as endophthalmitis, is uncommon in HIV-infected patients. We report a case of candidal endophthalmitis in an HIV-positive non-drug-user patient, following candidemia from a cutaneous abscess at the site of a peripheral catheter. Ocular disease was revealed by a visual decrease in the left eye. DNA analysis using RAPD showed identical patterns of Candida albicans isolated from the skin and eye. Combination therapy with high-dose fluconazole and intravenous amphotericin B was performed. Two intravitreal amphotericin B injections and a vitrectomy were administered because of an amblyopic right eye and severe vitritis. The outcome was favorable without relapse at 18 months. |
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| Keywords: | Endophthalmitis candidal infection HIV |
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