| ICR和昆明种小鼠生物法检测麻痹性贝类毒素毒性差异比较 |
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| 引用本文： | 林健,黄宗锈,陈冠敏,林蔚,陈明中,林春芳.ICR和昆明种小鼠生物法检测麻痹性贝类毒素毒性差异比较[J].现代预防医学,2011,38(23):4937-4938,4942. |
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| 作者姓名： | 林健 黄宗锈 陈冠敏 林蔚 陈明中 林春芳 |
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| 作者单位： | 福建省疾病预防控制中心(福建省实验动物质量检测中心,福建医科大学公共卫生学院教学基地),福州,350001 |
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| 摘 要： | 目的]了解痹性贝类毒素小鼠生物法检测采用ICR和昆明神小鼠的差异. 方法]用平行法对ICR和昆明种小鼠进行了20个批次的织纹螺麻痹性贝类毒素生物法比对试验. 结果]两个品系动物试验结果的变异系数为8％,t检验结果表明两种品系动物的差异无统计学意义.两个品系动物比对试验结果表明具相关性且回归系数有显著性意义,但绝对值有一定的差异. 结论]ICR和昆明种小鼠痹性贝类毒素小鼠生物法检测结果具有很强的相关性和线型关系,但在两组数值的绝对值的差异值得关注.
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| 关 键 词： | 麻痹性贝类毒素 ICR小鼠 昆明种小鼠 |
COMPARISON OF ICR AND KM MICE USED IN BIOLOGICAL EXAMINATION OF PARALYTIC SHELLFISH POISON |
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| LIN Jian,HUANG Zong-xiu,CHEN Guan-min,et al..COMPARISON OF ICR AND KM MICE USED IN BIOLOGICAL EXAMINATION OF PARALYTIC SHELLFISH POISON[J].Modern Preventive Medicine,2011,38(23):4937-4938,4942. |
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| Authors: | LIN Jian HUANG Zong-xiu CHEN Guan-min |
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| Institution: | LIN Jian,HUANG Zong-xiu,CHEN Guan-min,et al.(Fujian Center for Disease Control and Prevention,Fuzhou 350001,China) |
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| Abstract: | Objective]To compare the difference of ICR and KM mice used in biological examination of paralytic shellfish poison.Methods]ICR and KM mice were parallel used in biological examination of paralytic shellfish poison for 20 Nassarius Sp samples to compare their differences.Results]The coefficient of variation between two species was 8%.T test showed no significant difference between two species.Results of two species were relative and the regression coefficient was significant.Conclusion]Results of ICR an... |
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| Keywords: | Paralytic shellfish poison ICR mice KM mice |
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