| 辛伐他汀治疗高血压伴颈动脉硬化患者64例临床观察 |
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| 引用本文： | 陈向东,杨鹏麟. 辛伐他汀治疗高血压伴颈动脉硬化患者64例临床观察[J]. 现代预防医学, 2011, 38(24): 5154-5155,5158 |
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| 作者姓名： | 陈向东 杨鹏麟 |
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| 作者单位： | 浙江省温州医学院附属第二医院心血管内科,温州,325000 |
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| 摘 要： | [目的]探讨辛伐他汀治疗高血压伴颈动脉硬化患者的临床效果.[方法]64例高血压伴颈动脉硬化患者随机分为两组:辛伐他汀组采用辛伐他汀20 mg/d+常规治疗,对照组采用常规治疗,于治疗前后6周分别测定hsCRP、TC、TG及LDL-C等指标；高频超声检测颈动脉,记录颈动脉内膜中膜厚度(IMT)、颈动脉斑块积分、斑块发生率.[结果]辛伐他汀组治疗6周后TC、TG、LDL-C、hsC-RP、颈动脉内膜中膜厚度(IMT)、颈动脉斑块积分、斑块发生率较治疗前显著下降,差异有统计学意义(P＜0.05).[结论]辛伐他汀治疗可改善高血压伴动脉硬化患者动脉硬化程度及炎症反应的程度,具有稳定斑块的作用.
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| 关 键 词： | 辛伐他汀 高血压 血脂 |
PRIMARILY APPROACH TO BLOOD VESSEL MANAGEMENT PROBLEMS IN PATIENTS WITH HYPERTENTION IN BASIC LEVEL HOSPITALS |
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| CHEN Xiang-dong , YANG Peng-lin. PRIMARILY APPROACH TO BLOOD VESSEL MANAGEMENT PROBLEMS IN PATIENTS WITH HYPERTENTION IN BASIC LEVEL HOSPITALS[J]. Modern Preventive Medicine, 2011, 38(24): 5154-5155,5158 |
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| Authors: | CHEN Xiang-dong YANG Peng-lin |
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| Affiliation: | CHEN Xiang-dong,YANG Peng-lin.(Wenzhou Medical College,Wenzhou 325000,China) |
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| Abstract: | [Objective]Explore the feasibility of simvastatin therapy on preclinical Atherosclerosis in basic level hospitals.[Methods]64 hypertention patients combining atherosclerosis of carotid arteries were selected and were randomly divided into two groups;32 patients were involved as simvastatin group treated with simvastatin 20 mg/d and conventional therapy for six weeks. Others only treated by conventional therapy as control were convention group.Above all,not only serum levels of TC,TG,LDL-C and hs- CRP of all... |
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| Keywords: | Simvastatin Hypertention Serum lipide |
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